PMID: 12598493Feb 25, 2003Paper

A ten year, multicentre study of coagulase negative staphylococcal infections in Australasian neonatal units

Archives of Disease in Childhood. Fetal and Neonatal Edition
D Isaacs, Australasian Study Group For Neonatal Infections

Abstract

To study late onset systemic infections with coagulase negative staphylococci. Prospective longitudinal study of coagulase negative staphylococcal infection in 18 Australasian neonatal nurseries. From 1991 to 2000 inclusive, there were 1281 cases of coagulase negative staphylococcal (CoNS) sepsis, comprising 57.1% of all late onset infections. The male/female ratio was 1.27:1 (p < 0.05). The incidence of CoNS sepsis was 3.46 episodes per 1000 live births. Most infected babies (71%) were 24-29 weeks gestation at birth (mode 26 weeks). The first positive culture was day 7-14 in 49% of babies (mode 10 days). Five cases of meningitis were reported, an incidence of 0.4% of all CoNS infections. Twenty nine babies (2.3%) had concurrent necrotising enterocolitis and CoNS septicaemia. Four babies (0.3%) died from CoNS infection, but CoNS infection possibly contributed to the death of an additional 20 babies (1.6%). The mortality directly attributable to CoNS infection was significantly lower than that from late onset infections with Staphylococcus aureus (13.1%; relative risk (RR) = 36.1 (95% confidence interval (CI) 13.0 to 100.2) or with Gram negative bacilli (14.2%; RR = 45.5 (95% CI 16.8 to 123.3)). CoNS are currently responsible fo...Continue Reading

References

May 1, 1989·American Journal of Diseases of Children·J GruskayS Baumgart
Sep 1, 1987·The Journal of Hospital Infection·D IsaacsE R Moxon
Jan 1, 1988·Journal of Pediatric Surgery·D L MollittJ L Talbert
Apr 1, 1987·The Pediatric Infectious Disease Journal·R T HallI Zorbas
Aug 1, 1994·The Pediatric Infectious Disease Journal·S GuptaI H Gewolb
Sep 1, 1994·Archives of Disease in Childhood. Fetal and Neonatal Edition·M B SynnottS M Hall
Jul 1, 1993·Archives of Disease in Childhood·L HristevaA R Wilkinson
Oct 1, 1995·The Journal of Hospital Infection·P C NgK Liu
Apr 1, 1996·Journal of Paediatrics and Child Health·D IsaacsM Wong
Dec 29, 1998·Clinical Pediatrics·S A PearlmanJ D Klein
Feb 24, 2001·Archives of Disease in Childhood. Fetal and Neonatal Edition·D E HoltD Harvey

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Citations

Jun 3, 2010·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M BjörkqvistB Söderquist
Jul 7, 2011·Current Infectious Disease Reports·Rajesh K AnejaJoseph A Carcillo
Apr 14, 2012·Journal of Perinatology : Official Journal of the California Perinatal Association·C M HealyM S Edwards
Dec 21, 2013·Journal of Perinatology : Official Journal of the California Perinatal Association·B AlshaikhR Sauve
May 6, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Christopher J Crnich, Dennis G Maki
May 29, 2004·Current Opinion in Infectious Diseases·Leonard E Weisman
Jan 6, 2006·The Pediatric Infectious Disease Journal·Adrienne Gordon, David Isaacs
Jan 26, 2011·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Marieke A C HemelsTannette G Krediet
Jul 19, 2012·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Marieke A HemelsFloris Groenendaal
Jul 5, 2007·Current Opinion in Infectious Diseases·Tobias StrunkDavid Burgner
Feb 25, 2010·Current Opinion in Infectious Diseases·Gordon Y C Cheung, Michael Otto
Mar 2, 2013·Current Opinion in Infectious Diseases·Tobias StrunkDavid Burgner
Apr 23, 2005·Archives of Disease in Childhood. Fetal and Neonatal Edition·S VergnanoP T Heath
Dec 20, 2007·Pediatric Research·Catherine J HunterVictoria Camerini
Jul 19, 2013·PloS One·Carlos Alberto Pires PereiraUNKNOWN Brazilian SCOPE Study Group
Sep 26, 2013·Journal of Tropical Pediatrics·Suresh RamasamyBetsy Mathai
Nov 13, 2014·International Journal of Microbiology·Rania Mohammed KishkNader Attia Nemr
Sep 7, 2007·Journal of Perinatology : Official Journal of the California Perinatal Association·C Gras-Le GuenD Lepelletier
Dec 14, 2011·International Journal of Pediatrics·Sindhu SivanandanKamala Swarnam
Jan 12, 2011·European Journal of Pediatrics·Nehama LinderItzhak Levy
Dec 3, 2015·The Journal of Antimicrobial Chemotherapy·Julia A BielickiUNKNOWN Antibiotic Resistance and Prescribing in European Children project
Jul 15, 2015·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Brian A DarlowKeith Grimwood
Dec 1, 2009·The Journal of Infection·Cristiane Silveira de BritoPaulo P Gontijo Filho
Apr 22, 2009·The Journal of Hospital Infection·A W Gill, UNKNOWN Australian and New Zealand Neonatal Network
Nov 3, 2007·Seminars in Fetal & Neonatal Medicine·Nicholas D Embleton, Rowena Yates
Jan 9, 2013·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Tatjana BrileneIrja Lutsar
Sep 6, 2013·Pediatrics International : Official Journal of the Japan Pediatric Society·Hilal OzkanMustafa Hacımustafaoglu
Nov 3, 2004·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·F CampeottoJ Raymond
Aug 29, 2006·Seminars in Pediatric Infectious Diseases·Mohan P VenkateshLeonard E Weisman
Jun 15, 2011·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Naomi Jean-BaptisteP Brian Smith
Jun 3, 2014·International Journal of Medical Microbiology : IJMM·Ying Dong, Christian P Speer
Jul 18, 2015·Pediatric Research·Elizabeth A MarchantPascal M Lavoie

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