A ten year review of atrioventricular septal defects

Cardiology in the Young
Kathryn A DunlopDennis J Gladstone


To review all cases of atrioventricular septal defects in Northern Ireland from January 1990 to February 1999, examining clinical and morphological features, management, and outcome. A retrospective case note analysis of 106 subjects with comparisons between subgroups. An atrioventricular septal defect was part of a more complex abnormality in 50 of the patients (47%). Down's syndrome was present in 57 (54%). Cardiac surgery was performed in 81%. The defects were unrestrictive in 69 patients (65%), 45 of whom had Down's syndrome. Complex associated abnormalities existed in 36 patients, and 10 of these died without cardiac surgery. Operative mortality was 9.5% for those with co-existing Down's syndrome group, and 14.3% for the chromosomally normal patients. The ventricular components of the septal defect were restrictive in 23 patients (22%), with 9 having Down's syndrome. Spontaneous closure occurred in more than half of these patients. Mortality was zero. The septal defect was exclusively at atrial level in 14 patients ("primum" defects--13%), and 3 of these had Down's syndrome. Operative mortality was again zero. Median duration of postoperative follow-up was 3 and a half years. Overall, moderate to severe left atrioventricul...Continue Reading


Jun 15, 1991·BMJ : British Medical Journal·T R TubmanN C Nevin
Nov 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·K BandoR A Hurwitz
Jul 1, 1995·Archives of Disease in Childhood·J V FreemanM A Preece
Feb 1, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·G StellinD Casarotto

❮ Previous
Next ❯


Aug 26, 2009·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D PaladiniC Nappi
Oct 18, 2015·International Journal of Cardiology·Emmeline E CalkoenMonique R M Jongbloed
Sep 21, 2011·American Journal of Medical Genetics. Part a·Jeannie VisootsakStephanie L Sherman
Mar 28, 2006·The Annals of Thoracic Surgery·Yong-Qiang LaiZhao-Guang Zhang
Aug 25, 2010·The Annals of Thoracic Surgery·Hunaid A VohraMarcus P Haw
Dec 20, 2007·Annals of Human Biology·A H Bittles
Jul 9, 2004·Cardiology in the Young·Tjark Ebels, J William Gaynor
Feb 17, 2015·Cardiology in the Young·Jeannie VisootsakJessica Hunter

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.


Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.


Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

Practical Neurology
Victor Patterson
Health Visitor
C Jackson, T Haughey
Nursing Mirror and Midwives Journal
N J Hill
© 2021 Meta ULC. All rights reserved