A tertiary care center's experience with therapeutic hypothermia after pediatric cardiac arrest.

Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Ericka L FinkR Scott Watson

Abstract

To describe the use and feasibility of therapeutic hypothermia after pediatric cardiac arrest. Retrospective cohort study. Pediatric tertiary care university hospital. Infants and children (age 1 wk to 21 yrs) without complex congenital heart disease with return of spontaneous circulation after in-hospital or out-of-hospital cardiac arrest from 2000 to 2006. None. We studied 181 patients after cardiac arrest, of which 91% were asphyxial in etiology (vs. cardiac) and 52% occurred in-hospital. Overall survival to hospital discharge was 45%. Forty patients received therapeutic hypothermia; all were admitted during or after 2002. Sixty percent of patients in the therapeutic hypothermia group had an initial temperature <35 degrees C. The median therapeutic hypothermia target temperature was 34.0 degrees C (33.5-34.8 degrees C), was reached by 7 hrs (5-8 hrs) after admission in patients who were not hypothermic on admission, and was maintained for 24 hrs (16-48 hrs). Re-warming lasted 6 hrs (5-8 hrs). In the therapeutic hypothermia group, temperature <32 degrees C occurred in 15% of patients and was associated with higher hospital mortality (29% vs. 11%; p = .02). Patients treated with therapeutic hypothermia differed from those trea...Continue Reading

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