A test of genomic modularity among life-history adaptations promoting speciation with gene flow

Molecular Ecology
Gregory J RaglandJ L Feder

Abstract

Speciation with gene flow may require adaptive divergence of multiple traits to generate strong ecologically based reproductive isolation. Extensive negative pleiotropy or physical linkage of genes in the wrong phase affecting these diverging traits may therefore hinder speciation, while genetic independence or "modularity" among phenotypic traits may reduce constraints and facilitate divergence. Here, we test whether the genetics underlying two components of diapause life history, initial diapause intensity and diapause termination timing, constrain differentiation between sympatric hawthorn and apple-infesting host races of the fly Rhagoletis pomonella through analysis of 10,256 SNPs measured via genotyping-by-sequencing (GBS). Loci genetically associated with diapause termination timing were mainly observed for SNPs mapping to chromosomes 1-3 in the genome, most notably for SNPs displaying higher levels of linkage disequilibrium (LD), likely due to inversions. In contrast, selection on initial diapause intensity affected loci on all five major chromosomes of the genome, specifically those showing low levels of LD. This lack of overlap in genetically associated loci suggests that the two diapause phenotypes are largely modula...Continue Reading

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Citations

Jan 23, 2019·Evolution; International Journal of Organic Evolution·Glen R HoodScott P Egan
Dec 29, 2018·Molecular Ecology·Till CzypionkaLuc De Meester
Aug 4, 2020·Molecular Ecology·Jessica F McLaughlinKevin Winker
Sep 10, 2020·Proceedings of the National Academy of Sciences of the United States of America·Edwina J DowleGregory J Ragland
Jul 14, 2020·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Peter J MeyersJeffrey L Feder
Jan 8, 2021·Molecular Ecology·Tobias S KaiserDavid G Heckel
Feb 15, 2021·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Jantina ToxopeusGregory J Ragland
Sep 21, 2019·Current Opinion in Insect Science·Gregory J RaglandMegan E Meuti
May 22, 2019·Current Opinion in Insect Science·Meredith M Doellman, Jeffrey L Feder
Jun 17, 2021·Molecular Ecology·Jonathan M Waters, Graham A McCulloch

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