A theoretical model for lipid monolayer phase transitions.

Biochimica Et Biophysica Acta
H L Scott

Abstract

We present a theoretical model for the liquid-expanded to liquid-condensed phase transition observed in many phospholipid monolayer films. The total two-dimensional pressure in the model is the sum of the hydrocarbon chain pressure and the surface pressure. The hydrocarbon chain pressure is calculated in an exteded version of a model published earlier. The surface pressure results from a lowering of the surface tension in the monolayer over that of pure water, thus producing a force on a Langmuir float. When these two contributions are added, pi/A isotherms are obtained which have slope discontinuities very similar to those observed experimentally. The results indicate that a successful model for lipid phase behavior must consider the interactions between head groups and water as well as cooperative hydrocarbon chain melting.

References

Oct 29, 1974·Biochimica Et Biophysica Acta·S Marcelja
Apr 1, 1974·Chemistry and Physics of Lipids·P BothorelB Lemaire
Aug 13, 1974·Biochemistry·K R SrinivasanJ F Nagle

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Citations

Jan 1, 1981·Bio Systems·D S ChernavskiiA A Polezhaev
Nov 2, 1978·Biochimica Et Biophysica Acta·J F Nagle, H L Scott

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