A theoretical model for predicting interfacial relationships of retinal tamponades

Investigative Ophthalmology & Visual Science
Ian EamesAli Azarbadegan

Abstract

Purpose. To establish a theoretical model to determine the relationship between retinal coverage and tamponade shape in relation to tamponade volume, for a variety of tamponades, and to test these relationships with a physical analogue of the human eye. Methods. The theoretical model was based on a static balance between buoyancy forces and surface tension forces, for an axisymmetrically shaped bubble or droplet. In the laboratory experiments, two hemispheres were cut into an acrylic block. The acrylic was soaked with bovine serum for 10 minutes to ensure that the wetting properties were similar to the human retina. Photographic images of various fractions of lighter-than-water (gas, silicone) and heavier-than-water (Oxane HD) tamponades were analyzed by using algorithms written in commercial image-processing software and compared with the theoretical predictions and published data. Results. The theoretical predictions of tamponade shape and retinal coverage agree closely with the results obtained from the analogue experiments. Conclusions. The theoretical model was validated against measurements in a human eye analogue and published data. The three key parameters that characterize the retinal coverage of any given tamponade ar...Continue Reading

Citations

Oct 31, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Rachid Tahiri Joutei HassaniChristophe Baudouin
Aug 26, 2014·BioMed Research International·Krystyna IsakovaMario R Romano
Dec 20, 2015·Physical Biology·P NoohiY L Cheng
May 21, 2019·Translational Vision Science & Technology·Raul Velez-MontoyaEverardo Hernández-Quintela
Nov 19, 2019·Translational Vision Science & Technology·Jan O PralitsJavier Cabreizo
May 27, 2021·Eye·Mario R RomanoRodolfo Repetto
Jul 28, 2021·Translational Vision Science & Technology·Tommaso RossiGuido Ripandelli
Nov 14, 2021·Journal of Biomechanical Engineering·Ru WangD Ian Wilson

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