PMID: 531090Nov 1, 1979

A theoretical study of quantitative flow measurements with constant infusion of short-lived isotopes

Physics in Medicine and Biology
S C HuangD E Kuhl

Abstract

Recent developments in the technique of constant infusion and in emission computed tomography have provided a new method for quantitative regional flow measurements. This paper re-examines critically the theoretical relationship between flow and radioactivity during constant infusion of short-lived isotopes. Sensitivity analysis is used to assess the accuracy of the method. Criteria for the selection of an appropriate half-life to meet accuracy requirements are also discussed. A method for the determination of the distribution volume of the tracer is proposed.

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Sep 28, 1998·Cancer Chemotherapy and Pharmacology·A L BoralB A Chabner
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Related Concepts

Blood Circulation
Mathematics
Radioisotopes
Regional Blood Flow

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