A theoretical study on phase-contrast mammography with Thomson-scattering x-ray sources

Medical Physics
Liberato De CaroSabina Tangaro

Abstract

The x-ray transmitted beam from any material/tissue depends on the complex refractive index (n= 1-delta+ibeta), where delta is responsible for the phase shift and beta is for the beam attenuation. Although for human tissues, the delta cross section is about 1000 times greater than the beta ones in the x-ray energy range from 10 to 150 keV, the gain in breast tumor visualization of phase-contrast mammography (PCM) with respect to absorption contact imaging (AI) is limited by the maximum dose that can be delivered to the patient. Moreover, in-line PC imaging (PCI) is the simplest experimental mode among all available x-ray PCI techniques since no optics are needed. The latter is a fundamental requirement in order to transfer the results of laboratory research into hospitals. Alternative to synchrotron radiation sources, the implementation of relativistic Thomson-scattering (TS) x-ray sources is particularly suitable for hospital use because of their high peak brightness within a relatively compact and affordable system. In this work, the possibility to realize PCM using a TS source in a hospital environment is studied, accounting for the effect of a finite deliverable dose on the PC visibility enhancement with respect to AI. The ...Continue Reading

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Citations

Feb 5, 2013·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·F ScattarellaR Bellotti
Jun 2, 2011·Medical Physics·Liberato De CaroRoberto Bellotti
Jan 29, 2014·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Renata LongoMaria A Cova
Sep 14, 2010·Medical Physics·Liberato De CaroRoberto Bellotti
Dec 12, 2012·Physics in Medicine and Biology·Alberto BravinPekka Suortti

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