A theory of cellular-function pathology: further development of Virchow's theory of cellular pathology

Medical Hypotheses
A Yabrov

Abstract

A new theory of pathology is introduced. The human cell is an organism in itself. It fulfills both cell-oriented and organism-oriented functions. Impairment of either one of these functions may lead to disease. This means that a structural lesion of a cell is not a sole and necessary cause of the beginning of disease. When a cell-oriented function is impaired the cell suffers, but the overt symptoms at the organ-organism level might be absent for a very long time. This is how a chronic asymptomatic disease starts. Measures of prophylaxis, diagnosis, and treatment should be centered upon maintenance and restoration of a balance between the cell-oriented and organism-oriented cellular functions.

References

Mar 1, 1986·Medical Hypotheses·A Yabrov
Dec 1, 1986·Medical Hypotheses·A Yabrov
Jan 1, 1987·Medical Hypotheses·A Yabrov
May 1, 1985·Medical Hypotheses·A Yabrov
Aug 10, 1956·Science·O WARBURG

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Citations

Jun 15, 2004·Medical Hypotheses·Alexander Yabrov, Yuri Okunev
Feb 9, 2006·Anales de la Real Academia Nacional de Medicina·José Aguilar Peris

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