A three-year evaluation of hemostatic function in Singaporean Norplant-2 rod acceptors

Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception
K SinghS S Ratnam

Abstract

A longitudinal study of hemostatic function was carried out on 100 Singaporean acceptors using Norplant-2 rods for contraception. The results at the end of three years indicate a possible increased predisposition to thrombosis, as evidenced by significant increases in platelet count and aggregability. The prothrombin time (PT) and activated partial thromboplastin time (APTT) continued to remain shortened at the end of three years of use. There was also a general fall in most of the vitamin K coagulation factors. There is thus still an indication of a possible enhanced potential for hypercoagulation at the end of three years of Norplant-2 rod use.

References

Feb 15, 1967·American Journal of Obstetrics and Gynecology·F K Beller, R F Porges
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Citations

Sep 1, 1993·Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception·K SinghS S Ratnam
Feb 28, 2002·Contraception·Laneta J Dorflinger
Apr 1, 1996·NMR in Biomedicine·L L Hansen, J W Jaroszewski
Mar 26, 2003·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Irving Sivin

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