A time-domain wavelet-based approach for fluorescence diffuse optical tomography

Medical Physics
Nicolas DucrosFrançoise Peyrin

Abstract

In the context of fluorescence diffuse optical tomography, determining the optimal way to exploit the time-resolved information has been receiving much attention and different features of the time-resolved signals have been introduced. In this article, the authors revisit and generalize the notion of feature, considering the projection of the measurements onto some basis functions. This leads the authors to propose a novel approach based on the wavelet transform of the measurements. A comparative study between the reconstructions obtained from the proposed wavelet-based approach and the reconstructions obtained from the reference temporal moments is provided. An inhomogeneous cubic medium is considered. Reconstructions are performed from synthetic measurements assuming Poisson noise statistics. In order to provide fairly comparable reconstructions, the reconstruction scheme is associated with a particular procedure for selecting the regularization parameter. In the noise-free case, the reconstruction quality is shown to be mainly driven by the number of selected features. In the presence of noise, however, the reconstruction quality depends on the type of the features. In this case, the wavelet approach is shown to outperform t...Continue Reading

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Citations

Dec 11, 2013·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Wei ZouDavid Dagan Feng

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