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A-to-I RNA editing and cancer: from pathology to basic science

RNA Biology

Sep 2, 2008

Angela Gallo, Silvia Galardi

Abstract

In eukaryotes mRNA transcripts are extensively processed by different post-transcriptional events such as alternative splicing and RNA editing in order to generate many different mRNAs from the same gene, increasing the transcriptome and then the proteome. The most frequent RNA editing ...read more

Mentioned in this Paper

Enzymes, antithrombotic
Transcription, Genetic
Inosine
RNA Editing
Proteome
Substrate Specificity
Enzymes for Treatment of Wounds and Ulcers
Pathology
Malignant Neoplasms
Transcriptome
Paper Details
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A-to-I RNA editing and cancer: from pathology to basic science

RNA Biology

Sep 2, 2008

Angela Gallo, Silvia Galardi

PMID: 18758244

DOI: 10.4161/rna.5.3.6739

Abstract

In eukaryotes mRNA transcripts are extensively processed by different post-transcriptional events such as alternative splicing and RNA editing in order to generate many different mRNAs from the same gene, increasing the transcriptome and then the proteome. The most frequent RNA editing ...read more

Mentioned in this Paper

Enzymes, antithrombotic
Transcription, Genetic
Inosine
RNA Editing
Proteome
Substrate Specificity
Enzymes for Treatment of Wounds and Ulcers
Pathology
Malignant Neoplasms
Transcriptome

Similar Papers Found In These Feeds

RNA Splicing (Keystone)

The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. Discover the latest research on RNA splicing and co-transcriptional splicing in this feed.

Epigenome Engineering

Recent advances in epigenome engineering technologies allow now for the large-scale assessment of the functional relevance of dna methylation. Discover the latest research here.

Related Papers

RNA Biology

A-to-I RNA editing and human disease

RNA BiologyNovember 23, 2006
Stefan MaasKazuko Nishikura
Proceedings of the National Academy of Sciences of the United States of America

Underediting of glutamate receptor GluR-B mRNA in malignant gliomas

Proceedings of the National Academy of Sciences of the United States of AmericaNovember 22, 2001
Stefan MaasA Rich
Paper Details
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  • Citations32
  • finger pointing at paper

    References currently unavailable

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  • References
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