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A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer

Cancer Cell

May 1, 2018

Xinxin PengGordon B Mills

Abstract

Adenosine (A) to inosine (I) RNA editing introduces many nucleotide changes in cancer transcriptomes. However, due to the complexity of post-transcriptional regulation, the contribution of RNA editing to proteomic diversity in human cancers remains unclear. Here, we performed an integra...read more

Mentioned in this Paper

Study
Gene Expression Regulation, Neoplastic
Post-Transcriptional Regulation
Adenosine
Genome
Cell Motility
Sequence Determinations, RNA
Inosine
Neoplasms
Tandem Mass Spectrometry
57
7
1
108
1
Paper Details
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A-to-I RNA editing does not change with age in the healthy male rat brain

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A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer

Cancer Cell

May 1, 2018

Xinxin PengGordon B Mills

PMID: 29706454

DOI: 10.1016/j.ccell.2018.03.026

Abstract

Adenosine (A) to inosine (I) RNA editing introduces many nucleotide changes in cancer transcriptomes. However, due to the complexity of post-transcriptional regulation, the contribution of RNA editing to proteomic diversity in human cancers remains unclear. Here, we performed an integra...read more

Mentioned in this Paper

Study
Gene Expression Regulation, Neoplastic
Post-Transcriptional Regulation
Adenosine
Genome
Cell Motility
Sequence Determinations, RNA
Inosine
Neoplasms
Tandem Mass Spectrometry
57
7
1
108
1

Similar Papers Found In These Feeds

Proteogenomics

Proteogenomics is a multi-omics research field that has the aim to efficiently integrate genomics, transcriptomics and proteomics. Here is the latest research on proteogenomics.

Chemoproteomics

Chemoproteomics is an approach to discovering mechanisms for regulating biological pathways for the purpose of designing new pharmaceutical therapies. Here is the latest research on this chemical proteomic method for pharmacological discovery research.

Related Papers

Biogerontology

A-to-I RNA editing does not change with age in the healthy male rat brain

BiogerontologyMay 28, 2013
Andrew P HolmesJoão Pedro de Magalhães
Progress in Nucleic Acid Research and Molecular Biology

ADAR gene family and A-to-I RNA editing: diverse roles in posttranscriptional gene regulation

Progress in Nucleic Acid Research and Molecular BiologyAugust 13, 2005
Louis Valente, Kazuko Nishikura
Paper Details
References
  • References
  • Citations11
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations11
12
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