PMID: 8970927Jan 1, 1997Paper

A triphasic analysis of negative osmotic flows through charged hydrated soft tissues

Journal of Biomechanics
W Y GuV C Mow

Abstract

Osmotic flow and ion transport in a one-dimensional steady diffusion process through charged hydrated soft tissues such as articular cartilage were analysed using the triphasic theory (Lai et al., 1991, J. biomech. Engng 113, 245-258). It was found that solvent would flow from the high NaCl concentration side to the low concentration side (i.e. negative osmosis) when the fixed charge density within the tissue (or membrane) separating the two electrolyte (NaCl) solutions was lower than a critical value. The condition for negative osmosis was derived based on a linear version of the triphasic theory. Distributions of ion concentration and strain field within the tissue were calculated numerically. Quantitative results of osmotic flow rates (ordinary and negative osmosis), ion flux and electric potential across the tissue during this diffusion process suggest that the negative osmosis phenomenon is due to the friction between ions and water since they could flow through the tissues at different rates and different directions.

References

Aug 1, 1991·Journal of Biomechanical Engineering·W M LaiV C Mow
Jan 1, 1985·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·S R Eisenberg, A J Grodzinsky
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Nov 1, 1960·The Journal of General Physiology·E GRIM, K SOLLNER
Sep 1, 1961·The Journal of General Physiology·O KEDEM, A KATCHALSKY

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Citations

Jan 9, 2007·Biomechanics and Modeling in Mechanobiology·Gerard A Ateshian
Apr 6, 2007·Journal of Biomechanical Engineering·Preethi L Chandran, Victor H Barocas
Mar 12, 2009·Journal of Biomechanical Engineering·J M HuygheK Malakpoor
Sep 29, 2011·Journal of Biomechanical Engineering·Gerard A AteshianJeffrey A Weiss
Oct 21, 2011·Journal of Biomechanical Engineering·Tai-Yi YuanWei Yong Gu
Aug 20, 2009·Journal of Cell Science·Guillaume T CharrasL Mahadevan
Aug 4, 2009·International Journal of Oral and Maxillofacial Surgery·W-J SeongC-C Ko
Aug 12, 2008·The Veterinary Journal·T AmitR Shahar
Apr 9, 2008·Seminars in Cell & Developmental Biology·T J MitchisonL Mahadevan
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Dorrit W Nitzan
Sep 14, 2011·Journal of Biomedical Materials Research. Part a·Spencer P LakeVictor H Barocas
Jan 31, 2007·IEEE Transactions on Bio-medical Engineering·Min-Hua LuQing-Hua Huang
Jul 19, 2002·Biophysical Journal·Guillaume T Charras, Mike A Horton
Nov 22, 2011·Journal of the Mechanical Behavior of Biomedical Materials·Franck J Vernerey, Mehdi Farsad
Mar 8, 2012·Tissue Engineering. Part a·Xiaofeng CuiDarryl D D'Lima
Aug 25, 2015·Journal of Biomechanical Engineering·Semih E BezciGrace D O'Connell
Jun 19, 2013·Journal of Biomechanical Engineering·Gerard A AteshianJeffrey A Weiss
Oct 24, 2018·Tissue Engineering. Part B, Reviews·Abdul Razzaq FarooqiUrsula van Rienen
Jul 29, 2008·Biomechanics and Modeling in Mechanobiology·W EhlersB Markert
Nov 5, 1999·Clinical Orthopaedics and Related Research·V C Mow, C C Wang
Jul 25, 2017·Biomechanics and Modeling in Mechanobiology·Tamer AbdalrahmanThomas Franz
Mar 23, 2021·Biophysics Reviews·Philip PoillotJacques M Huyghe

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