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A tug-of-war between driver and passenger mutations in cancer and other adaptive processes

bioRxiv

Feb 26, 2014

Christopher Dennis McFarlandKirill S. Korolev

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Abstract

Cancer progression is an example of a rapid adaptive process where evolving new traits is essential for survival and requires a high mutation rate. Precancerous cells acquire a few key mutations that drive rapid population growth and carcinogenesis. Cancer genomics demonstrates that the...read more

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Treatment Protocols
Tumor Cells, Malignant
Premalignant Cell
Mutation Abnormality
Population Group
Adaptation
EAF2 gene
Size
Tumor Progression
Research
9
4
Paper Details
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  • A tug-of-war between driver and passenger mutations in cancer and other adaptive processes

    bioRxiv

    Feb 26, 2014

    Christopher Dennis McFarlandKirill S. Korolev

    PMID: 990003053

    DOI: 10.1101/003053

    Abstract

    Cancer progression is an example of a rapid adaptive process where evolving new traits is essential for survival and requires a high mutation rate. Precancerous cells acquire a few key mutations that drive rapid population growth and carcinogenesis. Cancer genomics demonstrates that the...read more

    Mentioned in this Paper

    Treatment Protocols
    Tumor Cells, Malignant
    Premalignant Cell
    Mutation Abnormality
    Population Group
    9
    4
    Paper Details
    References
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      We're still populating references for this paper, please check back later.
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