A tumor microenvironment model coupled with a mass spectrometry system to probe the metabolism of drug-loaded nanoparticles

Chemical Communications : Chem Comm
Ling LinJin-Ming Lin

Abstract

This study describes a novel integrated microfluidic platform with microvessel network channels which are connected to an electrospray ionization-mass spectrometer (ESI-MS), allowing real-time probing of nanoparticle (NP) drug delivery in vascular niche around tumors and understanding the drug delivery efficacy in a realistic tumor microenvironment.

References

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Feb 3, 2018·Chemical Communications : Chem Comm·Qiushi HuangJin-Ming Lin
Sep 27, 2018·Chemical Communications : Chem Comm·Nan LiJin-Ming Lin

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