A Tutorial on Saliva's Role in Swallowing With a Focus on Sjögren's Syndrome.

American Journal of Speech-language Pathology
Veronica H LetawskyStacey A Skoretz

Abstract

Purpose Saliva is integral to swallowing and necessary for oral health. Understanding saliva's origin and properties is important for swallowing assessment and management. Diseases such as Sjögren's syndrome (SS) can affect saliva negatively, often contributing to dysphagia. Our objectives are to (a) highlight saliva's fundamental role in swallowing, (b) provide a bibliometric overview of literature pertaining to SS pathophysiology and effects on saliva, (c) explore implications of salivary changes on swallowing and quality of life in SS and other populations, and (d) provide suggestions for systematic saliva assessment in practice. Method This tutorial reviews saliva production, composition, and involvement in swallowing within health and disease. Using rapid review methodology, we outline the effect of SS on saliva and describe SS etiology, diagnosis, and treatment. We discuss formal saliva assessments and a multidisciplinary approach. Results Saliva plays a vital role in swallowing, particularly lubrication, bolus formation, and oral health. SS affects the salivary glands altering salivary flow rate and composition. We identified 55 studies (N) measuring salivary changes, grouping them according to four strata demarcated by ...Continue Reading

References

Feb 1, 1976·Oral Surgery, Oral Medicine, and Oral Pathology·I D Mandel, H Baurmash
Jun 1, 1984·Journal of Oral Pathology·R N StuchellH Baurmash
May 1, 1995·Archives of Oral Biology·J F Prinz, P W Lucas
Aug 1, 1996·European Journal of Oral Sciences·W A van der ReijdenA V Nieuw Amerongen
Apr 1, 1997·The British Journal of Oral & Maxillofacial Surgery·E A FieldW M Edgar
Feb 3, 1998·Proceedings. Biological Sciences·J F Prinz, P W Lucas
Feb 24, 2001·The Journal of Prosthetic Dentistry·S P Humphrey, R T Williamson
Mar 16, 2001·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·M MoodyI Al-Hashimi
Jun 16, 2001·Head & Neck·J A LogemannL A Newman
Nov 16, 2001·Annals of the Rheumatic Diseases·W W KalkA V Nieuw Amerongen
Jan 18, 2002·Annals of the Rheumatic Diseases·W W I KalkC G M Kallenberg
May 11, 2002·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·R Matsuo
May 15, 2002·Annals of the Rheumatic Diseases·C VitaliUNKNOWN European Study Group on Classification Criteria for Sjögren's Syndrome
Jun 6, 2003·The Annals of Otology, Rhinology, and Laryngology·Joseph DonzelliMary Craney
Jul 1, 2004·Archives of Internal Medicine·Stuart S Kassan, Haralampos M Moutsopoulos
Mar 9, 2005·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Ann Rose HammiMichele Zipp
May 27, 2006·Annals of the Rheumatic Diseases·J PijpeA Vissink
Oct 19, 2006·Archives of Medical Research·Mario García-CarrascoRicard Cervera
Dec 21, 2006·Archives of Oral Biology·Lina EngelenAndries van der Bilt
Feb 23, 2007·Journal of Dental Research·E ZussmanR M Nagler
Mar 3, 2007·Annals of the New York Academy of Sciences·Douglas A GrangerLaura R Stroud
Mar 3, 2007·Annals of the New York Academy of Sciences·Philip C Fox
Mar 14, 2007·Clinical Medicine : Journal of the Royal College of Physicians of London·Roshan Amarasena, Simon Bowman
Oct 20, 2007·Hormones and Behavior·Elana B GordisPenelope K Trickett
Oct 31, 2007·Arthritis and Rheumatism·Shen HuDavid T Wong
Jan 1, 2008·Arthritis and Rheumatism·Charles G HelmickUNKNOWN National Arthritis Data Workgroup
Mar 4, 2008·The Journal of the American Dental Association·Carol M StewartWestley H Reeves
Mar 26, 2008·Journal of Dental Research·S A MathewsR H Scofield
Apr 18, 2008·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Ilana KaplanAndy Wolff
Nov 6, 2008·Rheumatic Diseases Clinics of North America·Ava J Wu
Dec 9, 2009·Clinica Chimica Acta; International Journal of Clinical Chemistry·Kyohei HigashiKazuei Igarashi
Jun 8, 2010·Rheumatology·Yun Jong LeeYeong Wook Song
Jul 10, 2010·Arthritis Care & Research·Shen HuDavid T Wong
Jul 21, 2010·Implementation Science : IS·Rebecca GanannHelen Thomas
Oct 5, 2010·Australian Dental Journal·M S Hopcraft, C Tan
Oct 29, 2010·Dysphagia·Nicole M Rogus-Pulia, Jeri A Logemann
Feb 25, 2011·Acta otorrinolaringológica española·Laura Daniela Ruiz AllecAngel Israel Pérez García
Apr 19, 2011·Respiratory Care·Rachael L ParkeShay P McGuinness

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.