A twin study of congenital hemiplegia

Developmental Medicine and Child Neurology
R Goodman, E Alberman

Abstract

Twins were more than three times more common in a large sample of London children with congenital hemiplegia than in the general population. This over-representation of twins could largely be explained by their higher rate of preterm birth, though twin-specific risk factors, including the consequences of a co-twin's death in utero, may also have played a part. None of the 34 co-twins who survived infancy had hemiplegia or any other form of cerebral palsy. Among 155 siblings of singletons with congenital hemiplegia, no child had hemiplegia and only one had cerebral palsy. Perhaps it is chance rather then genetic liability or an adverse environment that primarily governs who does and does not become congenitally hemiplegic.

References

Dec 1, 1979·The Journal of Pediatrics·A A SchinzelJ R Miller
Jul 23, 1976·Science·B A Afzelius
Jan 1, 1990·Acta geneticae medicae et gemellologiae·K Yoshida, K Matayoshi
May 1, 1990·American Journal of Obstetrics and Gynecology·R BejarR Resnik
Nov 1, 1990·American Journal of Medical Genetics·B PettersonD Henderson
Jun 1, 1990·Archives of Disease in Childhood·P O PharoahL Rosenbloom
Mar 1, 1989·Acta paediatrica Scandinavica·B HagbergL von Wendt
Mar 1, 1988·Journal of Autism and Developmental Disorders·M B Jones, P Szatmari
Dec 1, 1987·International Journal of Epidemiology·T L BurnsR M Lauer
Aug 1, 1987·British Journal of Obstetrics and Gynaecology·D S SeidmanR Gale
Jul 10, 1986·The New England Journal of Medicine·K B Nelson, J H Ellenberg
Oct 1, 1986·The Journal of Pediatrics·J ZonanaM J Webb
Jan 1, 1987·Early Human Development·P L YudkinA R Wilkinson
Jul 1, 1969·Acta paediatrica Scandinavica·K H GustavsonG Sanner
Sep 1, 1983·Archives of Neurology·R A BergA M Kaplan
Dec 1, 1994·Archives of Disease in Childhood·J M Buckler, M Green
May 1, 1994·Developmental Medicine and Child Neurology·R Goodman
Nov 13, 1993·BMJ : British Medical Journal·B PettersonF Stanley
Jun 1, 1961·Archives of Disease in Childhood·E M RUSSELL
May 5, 1962·Nature·S G VANDENBERGA B McKUSICK

❮ Previous
Next ❯

Citations

May 18, 2004·Acta Obstetricia Et Gynecologica Scandinavica·Monica ToppUNKNOWN SCPE Collaborative Group
Nov 1, 1996·Archives of Disease in Childhood. Fetal and Neonatal Edition·K WilliamsE Alberman
Jun 8, 2001·Psychological Bulletin·M RutterL Eaves

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Related Papers

International Journal of Epidemiology
Y YokoyamaK Hayakawa
Archives of Disease in Childhood. Fetal and Neonatal Edition
P O D PharoahR Plomin
Developmental Medicine and Child Neurology
F J LaplazaP Cervera
© 2021 Meta ULC. All rights reserved