Abstract
To examine the long-term mortality experience of blacks who develop IDDM in childhood. The 11-25-year mortality status of individuals with IDDM who participated in the Diabetes Epidemiology Research International (DERI) Mortality Study was verified as of 1 January 1990 for 1,008 (94%) of the 1,076 individuals in the study. Life-table analysis was performed, and race-specific rates were determined for the final sample. Among black patients, 14.9% died compared with 6.6% of the white patients after a maximum of 25 years of follow-up. African-Americans experienced an age-adjusted mortality rate that was over twice that of whites for the entire period (9.4 vs. 3.8 per 1,000 person-years, respectively; P < 0.05) and at each 5-year interval of follow-up. Among blacks, the mortality rate for females (15.9/1,000 person-years) was 8.4 times (P < 0.05) that of males (1.9/1,000 person-years). In contrast, this sex difference was not seen among whites. Acute complications of diabetes accounted for 40% of the mortality in the black patients, while only 23% of the white patients died from acute causes. The data suggest that some of the excess mortality in black IDDM patients may be preventable.
Citations
Aug 26, 2000·Journal of Diabetes and Its Complications·S A ChalewA Vargas
Apr 16, 2002·Gut·T ZolfinoI G McFarlane
Mar 13, 2002·Ambulatory Pediatrics : the Official Journal of the Ambulatory Pediatric Association·D A ChristakisF A Connell
Jun 28, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Rimei NishimuraUNKNOWN Allegheny County Registry
Aug 5, 2011·Journal of Clinical Gastroenterology·Robert John WongCatherine Frenette
Sep 25, 2012·Diabetic Medicine : a Journal of the British Diabetic Association·R P DiasR Amin
May 20, 2011·The Journal of Pediatrics·Jenny T WangPerrin C White
Aug 21, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Sumita VermaPaul J Thuluvath
Jan 13, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·Z BosnyakT J Orchard
Jun 9, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·M RoyJ Skurnick
Aug 1, 2006·Diabetes Research and Clinical Practice·A BarcelóT Orchard
Jan 21, 2014·Diabetes Research and Clinical Practice·Raynard E WashingtonEugene S Tull
Aug 27, 2010·Diabetes·Aaron M SecrestTrevor J Orchard
May 12, 2001·Diabetes Care·R NishimuraT J Orchard
Aug 27, 2005·Diabetes Care·Loes C LantingAart H Bootsma
Jul 10, 2013·Diabetes Care·Baqiyyah Nilija ConwayWilliam James Blot
Apr 25, 2018·Journal of Diabetes and Its Complications·Kristi ReynoldsRichard F Hamman
Jun 18, 2021·Journal of Diabetes Science and Technology·Stuart ChalewLaurie Finger