PMID: 4507608Oct 1, 1972Paper

A unifying hypothesis concerning the nature of malignant growth

Proceedings of the National Academy of Sciences of the United States of America
R W Holley

Abstract

It is suggested that the crucial change in a malignant cell is an alteration in the cell surface membrane that results in increased internal concentrations of nutrients that regulate cell growth.

References

Nov 1, 1969·Proceedings of the National Academy of Sciences of the United States of America·D D Cunningham, A B Pardee
Nov 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·G S MartinH Rubin
Mar 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·K J Isselbacher
Mar 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·H Rubin
Feb 1, 1972·Journal of Cellular Physiology·A D Glinos, R J Werrlein
Nov 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·A LiptonR W Holley
Dec 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·B M Sefton, H Rubin

Citations

Jan 1, 1976·Journal of Supramolecular Structure·L Pickart, M M Thaler
Jan 1, 1977·Journal of Supramolecular Structure·M L Vilereal, J S Cook
Jan 1, 1977·Journal of Supramolecular Structure·C J Lobitz, M C Neville
Jan 1, 1977·Journal of Supramolecular Structure·G S Barsh, D D Cunningham
Jan 1, 1978·Journal of Supramolecular Structure·R MarzP G Plagemann
Jan 1, 1980·Journal of Cancer Research and Clinical Oncology·G RonquistB Westermark
Jul 5, 1977·Molecular and Cellular Biochemistry·N D Judewicz, H N Torres
May 1, 1979·In Vitro·A I Neugut, I B Weinstein
May 1, 1979·In Vitro·A I Neugut, I B Weinstein
Aug 1, 1992·Biological Trace Element Research·E D Weinberg
Mar 1, 1981·Biological Trace Element Research·E D Weinberg
Nov 16, 1973·Biochimica Et Biophysica Acta·A A Belmonte, J Swarbrick
Apr 1, 1974·Chemistry and Physics of Lipids·E V DyatlovitskayaL D Bergelson
Oct 15, 1976·Life Sciences·G J Hopkins, C E West
Oct 16, 1978·Life Sciences·R Wondergem, V R Potter
Nov 23, 1981·Life Sciences·D S Straus
Dec 1, 1985·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·S Baldwin, R S Parker
Dec 16, 1974·Biochimica Et Biophysica Acta·P G Plagemann, D P Richey
Nov 14, 1977·Biochimica Et Biophysica Acta·S Schuldiner, H R Kaback
Feb 4, 1979·Biochimica Et Biophysica Acta·P Rudland, L Jimenez de Asua
Dec 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·E Rozengurt, L Jimenez de Asua
Jun 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·B Reynafarje, A L Lehninger
Aug 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·S K Bose, B J Zlotnick
Jan 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·L J de AsuaR Dulbecco
Oct 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·R W HolleyJ A Kiernan
Dec 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·D Quinlan, J Hochstadt
Apr 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·A B Pardee
Aug 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·R W Holley, J A Kiernan
May 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·D QuinlanJ Hochstadt
May 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·M W Unger, L H Hartwell
Aug 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·J E Lever
May 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·P BhattacharyaS Basu
Jun 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·W L McKeehan, K A McKeehan
Sep 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·R Tauber, W Reutter
Mar 1, 1976·The Journal of Cell Biology·L E Malick, R Langenbach
Jan 1, 1974·Annals of the New York Academy of Sciences·R E Barnett, J Palazzotto
Jul 1, 1974·The Journal of Clinical Investigation·F G TobackL M Lowenstein
Jun 1, 1978·The Journal of Clinical Investigation·G H Bean, L M Lowenstein
Apr 1, 1994·In Vitro Cellular & Developmental Biology. Animal·J K ChenS S Lin
Sep 18, 1978·Biochimica Et Biophysica Acta·A Anders, F Anders
Aug 29, 1980·Biochemical and Biophysical Research Communications·G P StudzinskiM Trocola-Simchera
Dec 15, 1978·Biochimica Et Biophysica Acta·G G GuidottiG C Gazzola
Jan 21, 1977·Biochimica Et Biophysica Acta·E Rozengurt, W D Stein
May 22, 1975·Biochimica Et Biophysica Acta·R Langenbach
Jan 1, 1990·Drug Metabolism Reviews·E D Weinberg
Jul 1, 1990·The American Journal of the Medical Sciences·J F Di StefanoN Hagag
Nov 1, 1976·Journal of Cellular Physiology·G RonquistB Westermark
Jan 1, 1978·Biochimie·K M Yamada, J Pouyssegur
Apr 1, 1976·Archives of Biochemistry and Biophysics·W R Gallaher, H A Blough
Feb 1, 1975·Journal of Theoretical Biology·R W Olsen
Dec 1, 1976·Journal of Theoretical Biology·R M Shymko
Jul 1, 1974·Journal of Theoretical Biology·J L Sullivan, A Debusk
Apr 7, 1983·Journal of Theoretical Biology·K Tarumi, H Schwegler
Jun 1, 1981·Experimental Cell Research·J C MacMillan, D N Wheatley
May 1, 1977·Experimental Cell Research·K Mierzejewski, E Rozengurt
Jan 1, 1976·Experimental Cell Research·M Jullien, L Harel
Aug 6, 1973·Biochemical and Biophysical Research Communications·D Paul
Jun 1, 2011·Seminars in Nuclear Medicine·Samuel L RiceJason S Lewis
Oct 1, 1986·Medical Hypotheses·C M Macfarlane
Oct 1, 1985·Medical Hypotheses·G Caesar
Apr 4, 1978·Biochimica Et Biophysica Acta·J L Sullivan, A Debusk
Dec 1, 1979·Medical Hypotheses·D E Schumm, R H Matthews
Sep 1, 1979·Medical Hypotheses·D O Kasprisin, S Millner
Jul 1, 1976·Archives of Biochemistry and Biophysics·J P BaderN R Brown
Jan 1, 1979·Medical Hypotheses·L Libenson, M Jena
Nov 1, 1977·Medical Hypotheses·K Miller
Nov 1, 1977·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M Steinitz, G Klein
Dec 1, 1981·European Journal of Cancer & Clinical Oncology·M J Tisdale
Aug 1, 1987·Oral Surgery, Oral Medicine, and Oral Pathology·D MockJ Freeman
Mar 19, 1976·Biochimica Et Biophysica Acta·E M De RobertisH N Torres
Mar 21, 1977·Biochemical and Biophysical Research Communications·D S Kelley, V R Potter
Jan 1, 1983·Differentiation; Research in Biological Diversity·P E BallJ F Conscience
Jan 1, 1977·Differentiation; Research in Biological Diversity·D Yaffe, O Saxel
Aug 11, 1977·Differentiation; Research in Biological Diversity·G Brunner
Nov 17, 1975·Biochemical and Biophysical Research Communications·D L Sanioto, S Schreier
Nov 28, 1979·Biochemical and Biophysical Research Communications·M AuberyR Bourrillon
Mar 1, 1980·Analytical Biochemistry·D Barnes, G Sato
Dec 15, 1975·Biochemical and Biophysical Research Communications·E Rozengurt, L A Heppel
Mar 1, 1974·CRC Critical Reviews in Biochemistry·J Hochstadt
May 24, 1973·Experimental Eye Research·S J Socolar
Jan 1, 1979·Circulation Research·M B SiegelN G Levinsky
Sep 1, 1974·FEBS Letters·N D JudewiczH N Torres
Jul 26, 1974·Nature·I S Trowbridge, D A Hilborn
Oct 1, 1975·Journal of Neurochemistry·S E Geel, L K Gonzales
Feb 17, 2005·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·H Rubin
Apr 1, 1981·Journal of Cellular Physiology·M C Glassy, C E Furlong
Apr 1, 1979·Journal of Cellular Physiology·K D Nakamura, M J Weber
May 1, 1981·Journal of Cellular Physiology·R PrasadJ Hochstadt
Mar 1, 1985·Journal of Cellular Physiology·J S ZuzackS M DiZio
Nov 1, 1979·Journal of Cellular Physiology·M L Smith, J M Buchanan
May 1, 1982·Journal of Cellular Physiology·A H Romano, N D Connell
May 1, 1978·Journal of Cellular Physiology·J P BaderN R Brown
Dec 1, 1977·Journal of Cellular Physiology·R C Willis, J E Seegmiller
Dec 1, 1977·Journal of Cellular Physiology·M TramacereG G Guidotti
Sep 1, 1976·Journal of Cellular Physiology·B Mills, J T Tupper
Oct 1, 1980·Journal of Cellular Physiology·A F BorghettiG G Guidotti
Aug 1, 1979·Journal of Cellular Physiology·G F MerrillJ R Florini
Jun 1, 1985·Journal of Cellular Physiology·B McCaldin, E M Tenang
Nov 1, 1976·Journal of Cellular Physiology·S SpaggiareJ T Tupper
Feb 1, 1977·Journal of Cellular Physiology·D B BreenbergD D Cunningham
Feb 1, 1977·Journal of Cellular Physiology·T O Messmer, D V Young
Dec 1, 1976·Journal of Cellular Physiology·J Hochstadt, D Quinlan
Jan 1, 1976·Journal of Cellular Physiology·D A Hilborn
Apr 1, 1974·Journal of Cellular Physiology·Y Oshiro, J A DiPaolo
Feb 1, 1975·Journal of Cellular Physiology·C Colby, A H Romano
Feb 1, 1975·Journal of Cellular Physiology·D Paul, S Walter
Jul 1, 1977·Journal of Cellular Physiology·G S BarshD D Cunningham
Aug 1, 1977·Journal of Cellular Physiology·W P Naiditch, D D Cunningham
Nov 15, 1974·European Journal of Biochemistry·W Frank, H J Ristow
Aug 1, 1979·The Journal of Membrane Biology·A BabcockM Berman
Mar 8, 2006·Reproduction in Domestic Animals = Zuchthygiene·T H TsiligianniA Van Soom
Jan 1, 1981·Journal of Surgical Oncology·A A El-DomeiriW C Hsia
May 15, 1975·International Journal of Cancer. Journal International Du Cancer·M Siddiqi, P T Iype
Dec 14, 1979·Molecular and Cellular Biochemistry·A B Stavitsky, A A Gerblich
Jan 1, 1974·CRC Critical Reviews in Toxicology·R K Boutwell
Jan 1, 1980·CRC Critical Reviews in Biochemistry·J E Lever
Jun 23, 2016·Cold Spring Harbor Perspectives in Biology·Harold L MosesRik Derynck
Apr 29, 1974·Biochimica Et Biophysica Acta·M Hatanaka

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