A virulence-associated, 6.4-kb, double-stranded RNA from Rhizoctonia solani is phylogenetically related to plant bromoviruses and electron transport enzymes

Molecular Plant-microbe Interactions : MPMI
J H JianS M Tavantzis

Abstract

We have recently shown that acquisition of a 6.4-kb, double-stranded (ds) RNA (M1) by hyphal anastomosis is associated with enhanced vigor and virulence, whereas its removal by hyphal tipping correlates with diminished virulence in the plant-pathogenic basidiomycete Rhizoctonia solani. The M1 dsRNA is not encapsidated by a typical nucleocapsid, has a circular and/or concatemeric form, and is associated with the mitochondrial and cytosolic fractions. M1 possesses six open reading frames (ORFs) the longest of which (ORF 2) is located on the (+) strand, and encodes a putative polypeptide consisting of 1,747 amino acids or 199.4 kDa. This polypeptide has a significant amino acid sequence similarity, including six conserved helicase domains and an ATP/GTP binding motif, with the 1A protein of broad bean mottle virus (BBMV) and other bromoviruses. ORF 5, which is located on the (-) strand of M1 and is complementary to a region of ORF 2, codes for a putative polypeptide that has a significant amino acid sequence similarity with the cytochrome c oxidase assembly factor. This complementarity provides direct evidence suggesting that the long-standing hypothesis of viruses evolving from cellular genes may be valid.

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Citations

Nov 20, 2004·Virus Genes·Hideki Horiuchi, Toshiyuki Fukuhara
Apr 5, 2003·Journal of Invertebrate Pathology·Midori SugimotoHideyuki Nagao
Aug 3, 2005·Nature Reviews. Microbiology·Donald L Nuss
Aug 17, 2002·Molecular Plant-microbe Interactions : MPMI·Atsuko SasakiKouji Yoshida
Jul 9, 2014·Annual Review of Phytopathology·Jiatao Xie, Daohong Jiang
Feb 21, 2016·Fungal Biology·Subha DasAndrew R Pitman
Jun 10, 2003·Acta Microbiologica Et Immunologica Hungarica·J VargaC Vágvölgyi
Jan 27, 2017·Archives of Virology·Assane Hamidou AbdoulayeJiatao Xie
Jan 25, 2000·The Journal of General Virology·E E StraussS M Tavantzis
Dec 6, 2019·Viruses·Assane Hamidou AbdoulayeIoly Kotta-Loizou

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