A visible light photoredox catalyzed carbon radical-mediated generation of ortho-quinone methides for 2,3-dihydrobenzofuran synthesis

Chemical Communications : Chem Comm
Fan ZhouWen-Jing Xiao

Abstract

A visible light photoredox-catalyzed carbon radical-mediated strategy for in situ formation of ortho-quinone methides from 2-vinyl phenols is described. This strategy enables a multicomponent cyclization reaction of 2-vinyl phenols, Umemoto's reagent, and sulfur ylides, providing access to trifluoromethylated 2,3-dihydrobenzofurans.

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Citations

Aug 14, 2020·Chemical Communications : Chem Comm·Subramani Sangeetha, Govindasamy Sekar
Aug 10, 2021·Chemistry : a European Journal·Carlos Lázaro-Milla, Pedro Almendros
Nov 27, 2019·The Journal of Organic Chemistry·Gurdeep SinghRamasamy Vijaya Anand
Jul 20, 2019·The Journal of Organic Chemistry·Kenta TanakaKiyoshi Honda

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Methods Mentioned

BETA
NMR
X-ray

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