PMID: 9169827Mar 15, 1997Paper

A volumetric study of measurements and calculations of lung density corrections for 6 and 18 MV photons

International Journal of Radiation Oncology, Biology, Physics
E E KleinJ Matthews

Abstract

For treatment of lung cancer, dose heterogeneity corrections and subsequent prescription alteration remain controversial. Previous dosimetry studies based on slab geometry with a single beam geometry do not represent the clinical situation. A circumscribed tumor within lung poses a more complex problem. Energy choice also remains controversial. An anthropomorphic phantom was modified by replacing lung cylinders (2.5 and 5.0 cm diameters by 5.0 cm length) with muscle-equivalent cylinders. The phantom was scanned on a CT simulator. Gross, clinical, and planning target volumes (GTV, CTV, PTV1 including tumor and regional nodes, PTV2 including tumor only) were designated slice-by-slice. Three-dimensional planning was performed with large fields (AP/PA/RPO) covering PTV1 and boost fields optimized for each PTV2, for 6 and 18 MV photons. Homogeneous, Ratio-Tissue-Air-Ratio (RTAR), and convolution-adapted RTAR (CARTAR) calculation algorithms were tested. Film was placed between phantom slices at the "tumor" levels. The phantom was irradiated with monitor units corresponding to homogeneous calculations, based on a homogeneous prescription. Measured and calculated doses were compared by isodoses and dose volume histograms. Ionization ch...Continue Reading

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Citations

Nov 5, 2003·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Katrien De JaegerJoos V Lebesque
Jul 4, 2002·International Journal of Radiation Oncology, Biology, Physics·Ellen D YorkeChen-Shou Chui
Jul 20, 2002·International Journal of Radiation Oncology, Biology, Physics·Hidetoshi SaitohEtsuo Kunieda
Jul 23, 2003·International Journal of Radiation Oncology, Biology, Physics·Steven J FrankGeorge Starkschall
Jul 4, 1998·International Journal of Radiation Oncology, Biology, Physics·C G OrtonW T Sause
Jul 4, 1998·International Journal of Radiation Oncology, Biology, Physics·R C MillerR W Kline
Mar 31, 1999·International Journal of Radiation Oncology, Biology, Physics·M J BrugmansB J Mijnheer
Sep 14, 2012·Radiation Oncology·Laza RutonjskiJoanna Izewska
May 14, 2005·International Journal of Radiation Oncology, Biology, Physics·Charles W ScarantinoRobert D Black
Apr 19, 2006·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Miltiadis F TsiakalosKiki Theodorou
May 19, 2007·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·J LyonsA F Pruitt
May 27, 2004·Technology in Cancer Research & Treatment·Paul M DesRosiersLech S Papiez
May 22, 2009·Journal of Applied Clinical Medical Physics·Anneyuko I SaitoJames F Dempsey
Oct 25, 2001·Journal of Applied Clinical Medical Physics·M MiftenC M Ma

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