A weak balance: the contribution of muscle weakness to postural instability and falls

Nature Clinical Practice. Neurology
Corinne G C HorlingsBastiaan R Bloem

Abstract

Muscle strength is a potentially important factor contributing to postural control. In this article, we consider the influence of muscle weakness on postural instability and falling. We searched the literature for research evaluating muscle weakness as a risk factor for falls in community-dwelling elderly individuals, for evidence that strength training reduces falls, and for pathophysiological evidence from patients with neuromuscular disease that supports the link between muscle weakness and falls. In virtually all studies that included strength testing, muscle weakness was a consistent risk factor for falls in the elderly. Studies that evaluated the merits of muscle strength training often showed a reduction in fall rates, particularly when strength training was a component of a multifactorial intervention, although it was unclear whether strength training alone led to a fall reduction. Surprisingly few studies addressed the pathophysiological relationship between muscle strength and balance control. We conclude that muscle weakness is an important risk factor for falls that is potentially amenable to therapeutic intervention, and that future studies should further clarify the role of muscle weakness in balance control and t...Continue Reading

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References

Sep 1, 1992·American Journal of Epidemiology·G S Sorock, D M Labiner
Dec 1, 1991·Journal of the American Geriatrics Society·S R LordI W Webster
Dec 29, 1988·The New England Journal of Medicine·M E TinettiS F Ginter
Nov 1, 1988·Muscle & Nerve·R BarrettV Dubowitz
Sep 1, 1982·World Journal of Surgery·K SchwemmleW Padberg
Nov 1, 1995·Journal of the American Geriatrics Society·M E TinettiR Marottoli
Oct 1, 1994·Journal of the American Geriatrics Society·S R LordK J Anstey
Jun 1, 1994·Archives of Physical Medicine and Rehabilitation·S R Lord, S Castell
Sep 29, 1994·The New England Journal of Medicine·M E TinettiR I Horwitz
Feb 1, 1993·Annals of the Rheumatic Diseases·N D HopkinsonJ Lowe
Jan 1, 1993·Gerontology·R D ClarkI W Webster
May 1, 1996·Journal of the American Geriatrics Society·L WolfsonD Smyers
Jun 1, 1996·American Journal of Epidemiology·W C GraafmansP Lips
Feb 22, 1997·BMJ : British Medical Journal·M E McMurdoC R Paterson
Feb 1, 1997·Applied Nursing Research : ANR·R ToppJ Suhrheinrich
May 1, 1997·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·D S RooksW C Hayes
Jul 1, 1997·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·D M BuchnerE H Wagner
Feb 19, 1998·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·J M Shaw, C M Snow
May 20, 1999·Muscle & Nerve·M LaukJ J Collins
Jul 15, 1999·Journal of the American Geriatrics Society·J W DavisR D Wasnich
Jul 15, 1999·Journal of the American Geriatrics Society·A J CampbellD M Buchner
Feb 26, 2000·Age and Ageing·E ChuaA K Sharma
Mar 8, 2000·Experimental Brain Research·B R BloemF Honegger
Jun 8, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·L Z RubensteinA S Robbins
Jul 27, 2000·Medicine and Science in Sports and Exercise·M A van BaakF Hartgens
Jan 5, 2002·Journal of Neurology·B R BloemA H Zwinderman
Jun 6, 2002·Archives of Physical Medicine and Rehabilitation·Stephen R LordSimon C Gandevia
Jun 26, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·T UmapathiR Kuncl
Jul 20, 2002·BMJ : British Medical Journal·Lesley DayStephen Lord

❮ Previous
Next ❯

Citations

Oct 23, 2010·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·L M FeehanL C Li
Aug 25, 2009·European Journal of Applied Physiology·Paraskevi GiagazoglouElefthrerios Kellis
Jun 8, 2012·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Alfonso FasanoAlfredo Berardelli
Apr 16, 2013·Archives of Physical Medicine and Rehabilitation·Rafael MesquitaMartijn A Spruit
Apr 21, 2010·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Katri LihavainenSirpa Hartikainen
Dec 15, 2010·Journal of Neuroengineering and Rehabilitation·Agnes ZijlstraWiebren Zijlstra
Feb 8, 2014·Neurophysiologie clinique = Clinical neurophysiology·L Borel, B Alescio-Lautier
Jul 3, 2013·Clinical Orthopaedics and Related Research·Dana L JuddJennifer E Stevens-Lapsley
Mar 30, 2012·The Journal of Nutrition, Health & Aging·D BoersmaG Duque
Feb 18, 2016·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A W Frank-WilsonS A Kontulainen
Feb 24, 2016·BMC Sports Science, Medicine and Rehabilitation·K W DoumaW Zijlstra
Feb 6, 2016·Calcified Tissue International·Olivier Benichou, Stephen R Lord
Apr 29, 2015·Archives of Physical Medicine and Rehabilitation·Melissa MazzarinoMeg E Morris
Jan 9, 2016·Journal of Caring Sciences·Soubhagyalaxmi MohantyAlex Hankey
Sep 18, 2015·Human Movement Science·Longzhu Han, Feng Yang
Jun 12, 2012·Geriatrics & Gerontology International·Mitsuhiro AokiYatsuji Ito
Oct 25, 2016·The Laryngoscope·Nicole Tin-Lok JiamYuri Agrawal
Jul 21, 2015·Experimental Gerontology·Neal B McKinnonTimothy J Doherty
Oct 31, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Matti D AllenCharles L Rice
Feb 13, 2016·European Review of Aging and Physical Activity : Official Journal of the European Group for Research Into Elderly and Physical Activity·G Ruben H RegterschotWiebren Zijlstra
Jul 1, 2014·Pediatrics International : Official Journal of the Japan Pediatric Society·Pınar KayaHaluk Topaloğlu
Oct 3, 2009·Neuroscience·C G C HorlingsJ H J Allum
Feb 4, 2014·Parkinsonism & Related Disorders·Marjolein A van der MarckUNKNOWN NPF Falls Task Force
Nov 2, 2013·The Journal of Allergy and Clinical Immunology·Bjoern BuehringWilliam Busse
Dec 17, 2014·Journal of Biomechanics·Yi-Chung LinMarcus G Pandy
Jan 24, 2015·Neuromuscular Disorders : NMD·A BickerstaffeF Nollet
Jan 13, 2015·The Journal of Orthopaedic and Sports Physical Therapy·Kari Anne HakestadMay Arna Risberg
Oct 29, 2014·PloS One·L Eduardo Cofré LizamaJaap H van Dieën
Apr 16, 2011·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Robert C O'ReillyStephen Falcheck
Jul 22, 2017·Perceptual and Motor Skills·Helen Z WuJames J Grady

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