A Web-Based Human Papillomavirus Vaccination Intervention for Young Gay, Bisexual, and Other Men Who Have Sex With Men: Protocol for a Randomized Controlled Trial

JMIR Research Protocols
Paul L ReiterAnnie-Laurie McRee

Abstract

Gay, bisexual, and other men who have sex with men experience several disparities related to human papillomavirus (HPV) infection, including high incidence rates of anal cancer. Although the HPV vaccine is currently recommended for young adults, HPV vaccine coverage is modest among young gay, bisexual, and other men who have sex with men (YGBMSM). We describe the design and methods for a randomized controlled trial (RCT) to rigorously evaluate Outsmart HPV, a population-targeted, individually tailored, Web-based HPV vaccination intervention for YGBMSM. The RCT is designed to determine the efficacy of the intervention, the mechanism by which the intervention has an effect (ie, mediation), and whether efficacy varies by participant characteristics (ie, moderation). Outsmart HPV was previously developed and pilot-tested. This study is a 3-arm prospective RCT that will enroll a projected 1995 YGBMSM who are aged 18 to 25 years, live in the United States, and have not received any doses of the HPV vaccine. Participants will be recruited by means of paid advertisements on social media sites and randomized to receive (1) standard information on the Web about HPV vaccine (control group), (2) Outsmart HPV content on the Web with monthly...Continue Reading

Associated Clinical Trials

References

May 1, 1992·Psychological Bulletin·J D Fisher, W A Fisher
Nov 14, 2006·Sexually Transmitted Infections·J WallerJ Wardle
Jan 11, 2007·Journal of Medical Internet Research·Cameron D Norman, Harvey A Skinner
Jul 11, 2008·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Gypsyamber D'SouzaLisa P Jacobson
Aug 4, 2009·Journal of the National Cancer Institute·Anil K ChaturvediEric A Engels
Feb 2, 2010·Sexually Transmitted Diseases·Paul L ReiterJennifer S Smith
Aug 28, 2010·American Journal of Men's Health·Paul GilbertJennifer S Smith
May 18, 2011·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Jennifer S SmithJeanne M Pimenta
Aug 16, 2012·American Journal of Men's Health·Baudelio GutierrezAmy E Leader
May 3, 2014·Sexually Transmitted Infections·Tom NadarzynskiCarrie D Llewellyn
Jul 6, 2014·Shanghai Archives of Psychiatry·Douglas GunzlerHui Zhang
Nov 14, 2014·American Journal of Public Health·Paul L ReiterElectra D Paskett
Mar 31, 2015·American Journal of Preventive Medicine·Annika M HofstetterMelissa S Stockwell
Apr 8, 2015·The Journal of Law, Medicine & Ethics : a Journal of the American Society of Law, Medicine & Ethics·Jennifer E F TeitcherRobert L Klitzman
Feb 10, 2016·Sexually Transmitted Diseases·Mary A GerendBrian Mustanski
Jun 9, 2016·American Journal of Men's Health·Christopher W WheldonAnna R Giuliano
Feb 17, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ashish A DeshmukhArch G Mainous
Jun 16, 2017·Current Opinion in HIV and AIDS·José A BauermeisterLisa B Hightow-Weidman
Apr 2, 2019·AIDS Patient Care and STDs·Perry N HalkitisFarzana Kapadia

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NCT04032106

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