A Wolbachia infection from Drosophila that causes cytoplasmic incompatibility despite low prevalence and densities in males

Heredity
Kelly M RichardsonAry A Hoffmann

Abstract

Wolbachia bacteria are common insect endosymbionts transmitted maternally and capable of spreading through insect populations by cytoplasmic incompatibility (CI) when infected males cause embryo death after mating with uninfected females. Selection in the Wolbachia endosymbiont occurs on female hosts and is expected to favour strong maternal transmission to female offspring, even at the cost of reduced CI. With maternal leakage, nuclear genes are expected to be selected to suppress cytoplasmic incompatibility caused by males while also reducing any deleterious effects associated with the infection. Here we describe a new type of Wolbachia strain from Drosophila pseudotakahashii likely to have arisen from evolutionary processes on host and/or Wolbachia genomes. This strain is often absent from adult male offspring, but always transmitted to females. It leads to males with low or non-detectable Wolbachia that nevertheless show CI. When detected in adult males, the infection has a low density relative to that in females, a phenomenon not previously seen in Wolbachia infections of Drosophila. This Wolbachia strain is common in natural populations, and shows reduced CI when older (infected) males are crossed. These patterns highligh...Continue Reading

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Citations

Nov 22, 2019·FEMS Microbiology Letters·Sergio López-Madrigal, Elves H Duarte
Sep 11, 2019·Annual Review of Genetics·Perran A RossAry A Hoffmann
Oct 17, 2019·Parasites & Vectors·Arnab GhoshCorey L Brelsfoard
May 23, 2021·BMC Ecology and Evolution·Kay LucekJurriaan M de Vos

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Datasets Mentioned

BETA
MF348256
MF348261

Methods Mentioned

BETA
PCR
genotyping

Software Mentioned

Densitree
Geneious
Tracer
PartitionFinder
ape package
Treeannotator
[UNK] Analysis Pro
MEGA
LogCombiner
MLST

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