PMID: 9662025Jul 14, 1998Paper

A2rel: a constitutively expressed Leishmania gene linked to an amastigote-stage-specific gene

Molecular and Biochemical Parasitology
E GhedinG Matlashewski

Abstract

The A2-A2rel gene copies are arranged in tandem arrays on a 850 kb chromosome in Leishmania donovani. Contrary to A2 mRNA which displays amastigote-stage-specific expression, A2rel gene expression is constitutive throughout the L. donovani life cycle. The A2rel sequence was found to be conserved in all Leishmania species tested, while the A2 sequence is specific to L. donovani and L. mexicana. The A2rel full length cDNA is of 2.3 kb and it contains one open reading frame coding for a putative protein of 436 amino acids.

References

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May 5, 1982·Journal of Molecular Biology·J Kyte, R F Doolittle
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Aug 5, 1997·Proceedings of the National Academy of Sciences of the United States of America·W W Zhang, G Matlashewski

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Citations

Dec 29, 2012·BMC Genomics·Alejandro A AckermannFernán Agüero
Mar 30, 2005·BMC Infectious Diseases·Yves J F GarinFrédéric Lorenzo
Jul 27, 2001·Molecular Biology and Evolution·T A RawlingsR Bieler
Jun 28, 2003·The Journal of Biological Chemistry·Wen-Wei ZhangGreg Matlashewski
Apr 5, 2020·The Journal of Immunology : Official Journal of the American Association of Immunologists·Mukesh Kumar JhaBhaskar Saha
Nov 29, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Tim DowningGabriele Schönian

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