Abbreviated neuropsychological assessment in schizophrenia: prediction of different aspects of outcome.

Journal of Clinical and Experimental Neuropsychology
Philip D HarveyChristopher R Bowie

Abstract

The aim of this study was to identify the best subset of neuropsychological tests for prediction of several different aspects of functioning in a large (n = 236) sample of older people with schizophrenia. While the validity of abbreviated assessment methods has been examined before, there has never been a comparative study of the prediction of different elements of cognitive impairment, real-world outcomes, and performance-based measures of functional capacity. Scores on 10 different tests from a neuropsychological assessment battery were used to predict global neuropsychological (NP) performance (indexed with averaged scores or calculated general deficit scores), performance-based indices of everyday-living skills and social competence, and case-manager ratings of real-world functioning. Forward entry stepwise regression analyses were used to identify the best predictors for each of the outcomes measures. Then, the analyses were adjusted for estimated premorbid IQ, which reduced the magnitude, but not the structure, of the correlations. Substantial amounts (over 70%) of the variance in overall NP performance were accounted for by a limited number of NP tests. Considerable variance in measures of functional capacity was also ac...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Jan 1, 1987·Schizophrenia Bulletin·S R KayL A Opler
Jan 1, 1985·Schizophrenia Bulletin·R M BilderA K Pandurangi
Dec 1, 1981·Journal of Consulting and Clinical Psychology·R K Heaton, M G Pendleton
Jun 1, 1994·Archives of General Psychiatry·R HeatonD V Jeste
Mar 1, 1996·The American Journal of Psychiatry·M F Green
Dec 9, 1998·Journal of Clinical and Experimental Neuropsychology·C RandolphT N Chase
Mar 6, 1984·Social Work Research & Abstracts·L C Schneider, E L Struening
Oct 24, 2000·Schizophrenia Research·S R McGurk, H Y Meltzer
Feb 7, 2001·Archives of General Psychiatry·R K HeatonD V Jeste
Apr 11, 2001·Schizophrenia Research·T L PattersonD V Jeste
Feb 15, 2003·The Journal of Nervous and Mental Disease·Gary Bryson, Morris D Bell
Jul 29, 2003·Psychiatric Services : a Journal of the American Psychiatric Association·Susan R McGurkJoan Marder
Oct 12, 2004·Schizophrenia Research·Dawn I VelliganM Lynn Crismon
Oct 30, 2004·Journal of Clinical and Experimental Neuropsychology·Catherine L CareyUNKNOWN HNRC Group
Dec 14, 2004·The Clinical Neuropsychologist·Catherine L CareyUNKNOWN HNRC Group
May 13, 2005·Schizophrenia Bulletin·Christopher R BowiePhilip D Harvey
Feb 18, 2006·Journal of Clinical and Experimental Neuropsychology·Richard S E KeefePhilip D Harvey
Mar 4, 2006·The American Journal of Psychiatry·Robert RosenheckUNKNOWN CATIE Study Investigators Group
Apr 15, 2006·The Journal of Nervous and Mental Disease·Elizabeth W TwamleyRobert K Heaton
Apr 28, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Richard S E KeefeJeffrey A Lieberman
Oct 4, 2006·Journal of Psychiatric Research·Christopher R BowiePhilip D Harvey
Mar 8, 2007·Schizophrenia Bulletin·Brent T MausbachThomas L Patterson
Mar 24, 2007·Psychiatry Research·Dawn I VelliganAlexander L Miller
Jun 6, 2007·Archives of General Psychiatry·Richard S E KeefeUNKNOWN Neurocognitive Working Group
Nov 8, 2007·The American Journal of Psychiatry·Robert W BuchananRobert P McMahon
Apr 19, 2008·Journal of the International Neuropsychological Society : JINS·Winnie W LeungPhilip D Harvey

❮ Previous
Next ❯

Citations

Nov 4, 2011·The Journal of Nervous and Mental Disease·Colin A DeppBrent T Mausbach
Jun 28, 2011·Annals of General Psychiatry·Sofia BrissosMaria Luísa Figueira
Feb 11, 2014·Journal of Psychiatric Research·Gagan FervahaGary Remington
Aug 2, 2014·Journal of the International Neuropsychological Society : JINS·Eva MuharibNarmeen Ammari
Jul 30, 2014·Psychological Medicine·M LamR S E Keefe
Dec 22, 2009·Expert Review of Neurotherapeutics·S Kristian HillJohn A Sweeney
Jan 22, 2015·Acta Psychiatrica Scandinavica·V StergiopoulosS B Rourke
Oct 3, 2014·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Deanna M Barch, Julia M Sheffield
May 21, 2010·Schizophrenia Research·Pamela DeRosseAnil K Malhotra
Nov 1, 2013·Wiley Interdisciplinary Reviews. Cognitive Science·Philip D Harvey
Mar 1, 2014·Assessment·Warren B BilkerRuben C Gur
Nov 4, 2011·The Journal of Nervous and Mental Disease·Vicky StergiopoulosStephen Hwang
Aug 30, 2013·Journal of Clinical and Experimental Neuropsychology·Jennifer S HoBrent T Mausbach

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.