Abdominal adiposity and hot flashes among midlife women.

Menopause : the Journal of the North American Menopause Society
Rebecca C ThurstonKaren A Matthews

Abstract

Two competing hypotheses suggest how adiposity may affect menopausal hot flashes. The "thin hypothesis" asserts that aromatization of androgens to estrogens in body fat should be associated with decreased hot flashes. Conversely, thermoregulatory models argue that body fat should be associated with increased hot flashes. The study objective was to examine associations between abdominal adiposity and hot flashes, including the role of reproductive hormones in these associations. The Study of Women's Health Across the Nation Heart Study (2001-2003) is an ancillary study to the Study of Women's Health Across the Nation, a community-based cohort study. Participants were 461 women (35% African American, 65% white) ages 45 to 58 years with an intact uterus and at least one ovary. Measures included a computed tomography scan to assess abdominal adiposity; reported hot flashes over the previous 2 weeks; and a blood sample for measurement of follicle-stimulating hormone, estradiol, and sex hormone-binding globulin-adjusted estradiol (free estradiol index). Associations were evaluated within multivariable logistic and linear regression models. Every 1-SD increase in total (odds ratio [OR]=1.28; 95% CI: 1.06-1.55) and subcutaneous (OR=1.3...Continue Reading

References

May 1, 1992·The American Journal of Clinical Nutrition·C J LeyJ C Stevenson
Sep 14, 1999·Metabolism: Clinical and Experimental·K RäikkönenC H Bunker
Jan 20, 2000·International Journal of Biometeorology·G S Anderson
Mar 7, 2001·The Journal of Clinical Endocrinology and Metabolism·D M BermanA P Goldberg
Jul 19, 2002·JAMA : the Journal of the American Medical Association·Jacques E RossouwUNKNOWN Writing Group for the Women's Health Initiative Investigators
Nov 8, 2002·Archives of Physical Medicine and Rehabilitation·Jeffrey W OtteMitchell L Cordova
Jan 15, 2003·JAMA : the Journal of the American Medical Association·Melinda L IrwinAnne McTiernan
Jan 25, 2003·Menopause : the Journal of the North American Menopause Society·Howard M KravitzPeter M Meyer
Feb 11, 2003·Obstetrics and Gynecology·Maura K WhitemanJodi A Flaws
Feb 26, 2003·Metabolism: Clinical and Experimental·J A KanaleyL L Ploutz-Snyder
Jun 5, 2003·JAMA : the Journal of the American Medical Association·Vered StearnsEric Dube
Aug 14, 2003·American Journal of Epidemiology·Joyce T BrombergerAdriana Cordal
Dec 12, 2003·Metabolism: Clinical and Experimental·I GiannopoulouJ A Kanaley
Jan 13, 2004·Menopause : the Journal of the North American Menopause Society·UNKNOWN North American Menopause Society
Jan 28, 2005·Psychosomatic Medicine·Rebecca C ThurstonAndrew Sherwood
Apr 27, 2005·Seminars in Reproductive Medicine·Robert R Freedman
May 10, 2005·Menopause : the Journal of the North American Menopause Society·Ellen W FreemanTahmina Ferdousi
May 12, 2005·The Journal of Clinical Endocrinology and Metabolism·R E Van PeltW M Kohrt
Jul 23, 2005·Menopause : the Journal of the North American Menopause Society·Janet R GuthrieHenry G Burger
Sep 8, 2005·The Journal of Clinical Endocrinology and Metabolism·John F RandolphKaren A Matthews
Jan 18, 2006·The American Journal of Medicine·Sherry ShermanIsaac Schiff
Mar 31, 2006·Obesity·Kristi L StortiAndrea M Kriska
Dec 29, 2006·The Journal of Clinical Endocrinology and Metabolism·MaryFran SowersJames Symons

❮ Previous
Next ❯

Citations

Feb 28, 2009·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·A H E M Maas, H R Franke
Aug 20, 2011·Archives of Gynecology and Obstetrics·Suk Woo LeeJang Heup Kim
Jun 26, 2013·Breast Cancer Research and Treatment·Ikuyo ImayamaAnne McTiernan
Apr 30, 2010·American Journal of Epidemiology·Kim Sutton-TyrrellKaren Matthews
Mar 15, 2008·Menopause : the Journal of the North American Menopause Society·Nancy King Reame
Sep 10, 2008·Menopause : the Journal of the North American Menopause Society·Angela H E M Maas
Sep 1, 2008·Menopause : the Journal of the North American Menopause Society·Rebecca C ThurstonKaren A Matthews
Nov 27, 2008·Menopause : the Journal of the North American Menopause Society·Gerrie-Cor M GastYvonne T van der Schouw
Jul 16, 2009·Menopause : the Journal of the North American Menopause Society·Pauliina TuomikoskiOlavi Ylikorkala
Mar 11, 2010·Menopause : the Journal of the North American Menopause Society·Ellen W FreemanClarisa R Gracia
Nov 3, 2010·Menopause : the Journal of the North American Menopause Society·Angelo CagnacciAnnibale Volpe
Sep 20, 2011·Menopause : the Journal of the North American Menopause Society·Rebecca C ThurstonKaren A Matthews
Jul 12, 2012·Menopause : the Journal of the North American Menopause Society·Candyce H KroenkeRobert Wallace
Mar 28, 2013·Menopause : the Journal of the North American Menopause Society·Gerrie-Cor M Herber-GastAnnette J Dobson
Jul 23, 2011·The Journal of Clinical Endocrinology and Metabolism·Rebecca C ThurstonKaren A Matthews
Sep 14, 2010·Journal of Women's Health·Ayelet Ziv-Gal, Jodi A Flaws
Jun 16, 2011·Journal of Women's Health·Patricia G MoormanFrances Wang
Dec 8, 2010·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·José L CuadrosFaustino R Pérez-López
Jan 15, 2015·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Angelo CagnacciCostantino Di Carlo
Dec 3, 2011·Climacteric : the Journal of the International Menopause Society·I LambrinoudakiK Stamatelopoulos
Dec 7, 2011·Climacteric : the Journal of the International Menopause Society·A CagnacciA Volpe
Dec 9, 2008·Climacteric : the Journal of the International Menopause Society·M Andrikoula, G Prelevic
Aug 26, 2011·Climacteric : the Journal of the International Menopause Society·E RiescoI J Dionne
Oct 9, 2013·Climacteric : the Journal of the International Menopause Society·S M KujalaR J Kaaja
Dec 24, 2014·Climacteric : the Journal of the International Menopause Society·A CagnacciB Palmieri
Nov 12, 2015·Climacteric : the Journal of the International Menopause Society·S L GoughnourF Linkov
Mar 13, 2014·Fertility and Sterility·Zain A Al-Safi, Nanette Santoro
Jan 31, 2012·Maturitas·Thomas E Fisher, Judi L Chervenak
Oct 4, 2011·Obstetrics and Gynecology Clinics of North America·Rebecca C Thurston, Hadine Joffe
Oct 4, 2011·Obstetrics and Gynecology Clinics of North America·Rachel P Wildman, MaryFran R Sowers
Aug 30, 2011·Maturitas·Melissa K MelbyCarla Makhlouf Obermeyer
Apr 20, 2010·Maturitas·Gerrie-Cor M GastYvonne T van der Schouw
Apr 23, 2015·Menopause : the Journal of the North American Menopause Society·Ki-Jin RyuTak Kim
Feb 16, 2016·Current Obstetrics and Gynecology Reports·Lucy LiuAndrea R Hagemann
Mar 19, 2015·Menopause : the Journal of the North American Menopause Society·Lisa GallicchioJodi A Flaws
Jul 31, 2012·American Journal of Obstetrics and Gynecology·Ayelet Ziv-GalJodi A Flaws
Jan 13, 2015·Best Practice & Research. Clinical Obstetrics & Gynaecology·Zain A Al-Safi, Alex J Polotsky
May 7, 2016·Journal of Menopausal Medicine·Fatemeh ShobeiriSeyyed Mohammad Mahdi Hazavehei
Jun 5, 2016·Gastroenterology Clinics of North America·Octavia Pickett-BlakelyFarzana Rashid
Jun 14, 2016·Climacteric : the Journal of the International Menopause Society·J AbdulnourD Prud'homme

❮ Previous
Next ❯

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