Abdominal aortic aneurysm endovascular repair: profiling post-implantation morphometry and hemodynamics with image-based computational fluid dynamics

Journal of Biomechanical Engineering
Paola TassoUmberto Morbiducci

Abstract

Endovascular aneurysm repair (EVAR) has disseminated rapidly as an alternative to open surgical repair for the treatment of abdominal aortic aneurysms (AAAs), because of its reduced invasiveness, low mortality and morbidity rate. The effectiveness of the endovascular devices used in EVAR is always at question as postoperative adverse events can lead to re-intervention or to a possible fatal scenario for the circulatory system. Motivated by the assessment of the risks related to thrombus formation, here the impact of two different commercial endovascular grafts on local hemodynamics is explored through 20 image-based computational hemodynamic models of EVAR-treated patients (N=10 per each endograft model). Hemodynamic features, susceptible to promote thrombus formation, such as flow separation and recirculation, are quantitatively assessed and compared with the local hemodynamics established in image-based infrarenal abdominal aortic models of healthy subjects (N=10). The hemodynamic analysis is complemented by a geometrical characterization of the EVAR-induced reshaping of the infrarenal abdominal aortic vascular region. The findings of this study indicate that: (1) the clinically observed propensity to thrombus formation in de...Continue Reading

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Citations

Mar 7, 2019·International Journal for Numerical Methods in Biomedical Engineering·Huanming XuJiang Xiong
Jul 1, 2020·Computer Methods in Biomechanics and Biomedical Engineering·Javier DottoriIgnacio Larrabide
Aug 2, 2020·Annals of Vascular Surgery·Maurizio DomaninChristian Vergara
Feb 11, 2021·Cardiovascular Engineering and Technology·F BattistaM Taurino
Aug 23, 2019·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Anastasios RaptisMiltiadis Matsagkas

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