Abdominal aortic aneurysms - glycaemic status and mortality

Journal of Diabetes and Its Complications
Iren Drange HjellestadTorbjørn Jonung

Abstract

The prevalence of diabetes mellitus (DM) and mortality with respect to glycaemic status in patients with abdominal aortic aneurysms (AAA) was evaluated. Glycaemic status was assessed by an oral glucose tolerance test (OGTT) and by HbA1c. Sixty-six patients with AAA admitted to the vascular surgery unit for elective surgery between October 2006 and September 2007 were included. Seven patients had previously known DM. OGTT and HbA1c results were available from 58 patients. The patients were categorized as having DM, prediabetes and normoglycaemia according to the WHO's and American Diabetes Association's criteria. The prevalence of newly diagnosed DM according to the OGTT and HbA1c results were 12% and 14% respectively. Mean follow-up time was 68months and all-cause mortality 43%. HbA1c was an independent predictor for mortality in the DM category. Hazard ratio of all-cause mortality in the DM category defined by the HbA1c values was 6.35, 95% [CI 1.49-27.1]; p = 0.01. DM defined by HbA1c≥6.5% is an important determinant of mortality following surgical treatment for AAA. Half the patients with AAA and DM were unaware of their DM diagnosis. All patients with AAA should be tested for DM using HbA1c. The results should be confirmed ...Continue Reading

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Citations

Oct 31, 2017·Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease·Juliette Raffort, Fabien Lareyre
Jul 28, 2018·Cardiovascular Research·Juliette RaffortZiad Mallat
Nov 16, 2018·Biochemia Medica·Fabien LareyreJuliette Raffort
Apr 15, 2020·International Angiology : a Journal of the International Union of Angiology·Melissa Ribeiro-SilvaArmando Mansilha
May 31, 2019·Journal of Vascular Surgery·Fabien LareyreJuliette Raffort

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