PMID: 9548333Apr 21, 1998Paper

Abdominal metastases of pediatric brain tumors via ventriculo-peritoneal shunts

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
C H Rickert

Abstract

Internal drainage of cerebrospinal fluid (CSF) to the abdominal cavity via a ventriculo-peritoneal shunt (VPS) is a procedure that is commonly used for the treatment of obstructive hydrocephalus. As this condition is often caused by brain tumors blocking the natural CSF pathways, a VPS, as an artificial anastomosis, can provide the means for tumor cells to be spread with the CSF. A review of the literature reveals 35 VPS-related abdominal metastases from pediatric brain tumors; 17 in patients aged 0-9 (group A) and 18 in patients aged 10-18 years (group B); the mean age of male patients was 10.5, and that of female patients, 7 years. The male-to-female ratio was 1.9 (group A 1.1, group B 3.5), and the mean interval between shunt operation and diagnosis of metastases, 16.7 months (group A 11.6, group B 22.6 months; boys 21.6, girls 7.5 months). During the observation period, 22/30=73.3% of the patients died (group A 13/15=86.7%, group B 9/15=60%; boys 13/21=61.9%, girls 9/9=100%); their mean survival time after shunting was 18.7 months (group A 15.7, group B 23.1 months; boys 25.5, girls 9 months). The four most common sources of metastases were germinomas (9 cases=25.7%; group A none, group B 9), medulloblastomas (8 cases=22.9%...Continue Reading

Citations

May 11, 2004·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·R Shane TubbsW Jerry Oakes
Mar 28, 2007·Pediatric Surgery International·Rajendra Kumar GhritlahareyMonika Nanda
Oct 13, 2006·Current Treatment Options in Oncology·Jaishri O Blakeley, Stuart A Grossman
May 23, 2006·AJR. American Journal of Roentgenology·Ferdinando LoiaconoLuca Balestreri
Oct 27, 2007·Gynecologic Oncology·Yesim EralpErkan Topuz
Apr 20, 2011·British Journal of Neurosurgery·Matthew J MurrayG A Amos Burke
Jan 3, 2001·Microscopy Research and Technique·C H Rickert, W Paulus
Mar 8, 2003·Acta Neuropathologica·Christian H Rickert
Feb 2, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Chloé Louise GelderEric Bouffet
Jul 4, 2019·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Sean StephensRobert Campbell
Aug 24, 2021·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Philipp KarschniaJoerg-Christian Tonn

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