Abdominal obesity and hypertension: a double burden to the heart

Hypertension Research : Official Journal of the Japanese Society of Hypertension
Paweł KrzesińskiA Skrobowski

Abstract

Abdominal obesity (AO) is strongly associated with increased cardiovascular risk in hypertensives. Visceral adipose tissue has an important part in water retention, the sympathetic nervous system and renin-angiotensin-aldosterone system activation, which may influence central and systemic hemodynamics. The aim of this study was to estimate the relationship between AO and the hemodynamic profile of patients with arterial hypertension (AH). The clinical evaluation of 144 hypertensives included the following: (1) echocardiographic assessment of the left ventricular ejection fraction (LVEF), the global longitudinal systolic strain (GLSS) and diastolic function (E/A-phase ratio of mitral flow early (E) and late (A) and E/e'-ratio of early mitral flow and mitral septal annulus early diastolic velocity (e')); (2) the applanation tonometry including the central pulse pressure (CPP) and augmentation index (AI); and (3) the impedance cardiography, acceleration index (ACI), velocity index (VI), systemic vascular resistance index (SVRI) and total artery compliance (TAC). Obese hypertensives in comparison with non-obese ones were characterized with the following values: (1) lower echocardiographic (GLSS: -17.2±2.5% vs. -19.0±2.8%, P=0.0002)...Continue Reading

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Citations

Jan 27, 2017·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Ju Young JungJae-Hon Lee
Feb 10, 2017·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Shigehiko Ogoh
Oct 21, 2016·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Jessica E Middlemiss, Carmel M McEniery
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Nov 14, 2018·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Yuichi J Shimada
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