Abdominal obesity, insulin resistance, and the metabolic syndrome: contribution of physical activity/exercise

Obesity
Robert Ross, Jean-Pierre Després

Abstract

The metabolic syndrome, a constellation of metabolic abnormalities, which include abdominal obesity, insulin resistance, an atherogenic dyslipidemia, elevated blood pressure, a prothrombotic profile, and inflammation is associated with an increased risk of type 2 diabetes (1), cardiovascular disease (2), and mortality (3). The prevalence of individuals with these clustering abnormalities has been steadily increasing over the past two decades, is now estimated to affect at least a quarter of the US population, and is particularly prevalent among older adults (4). Similarly, abdominal obesity, as crudely estimated by an elevated waist circumference, is the most prevalent manifestation of the metabolic syndrome and affects 36% of men and 52% of women, according to the 1999-2000 US National Health and Nutrition Examination Study (5).

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Citations

Jul 7, 2011·Journal of Biosocial Science·Pilar Montero LópezSantiago Rodríguez López
Sep 28, 2010·Metabolism: Clinical and Experimental·Ashraf S GorgeyDavid R Gater
Jul 26, 2013·Thrombosis and Haemostasis·Mariangela MorelliAmalia Gastaldelli
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Jul 18, 2012·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Dae Yun SeoJin Han
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Jan 18, 2014·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Anne S GramElse-M Bladbjerg
Nov 9, 2016·Nutrition & Metabolism·Mélany PierardAlexandre Legrand
May 1, 2012·Expert Review of Endocrinology & Metabolism·Anne Q ReuwerVincent Goffin
Jan 6, 2021·International Journal of Molecular Sciences·Florian JuszczakAnne-Emilie Declèves

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