Abstract
The metabolic syndrome, a constellation of metabolic abnormalities, which include abdominal obesity, insulin resistance, an atherogenic dyslipidemia, elevated blood pressure, a prothrombotic profile, and inflammation is associated with an increased risk of type 2 diabetes (1), cardiovascular disease (2), and mortality (3). The prevalence of individuals with these clustering abnormalities has been steadily increasing over the past two decades, is now estimated to affect at least a quarter of the US population, and is particularly prevalent among older adults (4). Similarly, abdominal obesity, as crudely estimated by an elevated waist circumference, is the most prevalent manifestation of the metabolic syndrome and affects 36% of men and 52% of women, according to the 1999-2000 US National Health and Nutrition Examination Study (5).
References
Sep 1, 1978·American Journal of Epidemiology·R S PaffenbargerR T Hyde
Jul 18, 1991·The New England Journal of Medicine·S P HelmrichR S Paffenbarger
Mar 13, 1999·The American Journal of Clinical Nutrition·C D LeeA S Jackson
Mar 27, 2001·BMJ : British Medical Journal·J P DesprésD Prud'homme
Apr 24, 2001·Diabetes Care·B IsomaaL Groop
Jan 16, 2002·JAMA : the Journal of the American Medical Association·Earl S FordWilliam H Dietz
Dec 4, 2002·JAMA : the Journal of the American Medical Association·Hanna-Maaria LakkaJukka T Salonen
Aug 6, 2003·Medicine and Science in Sports and Exercise·Timo A LakkaJukka T Salonen
Oct 22, 2003·Obesity Research·Earl S FordWayne H Giles
Oct 28, 2003·Diabetes Care·Carlos LorenzoUNKNOWN San Antonio Heart Study
Jan 28, 2004·Circulation·Scott M GrundyUNKNOWN National Heart, Lung, and Blood Institute
Feb 6, 2004·Circulation·Scott M GrundyUNKNOWN American Diabetes Association
May 10, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·K G M M AlbertiJ Shaw
Jul 9, 2008·Annals of Medicine·Jean-pierre DesprésBenoit J Arsenault
Mar 31, 2009·Lancet·Jean-Pierre Després
Citations
Jul 7, 2011·Journal of Biosocial Science·Pilar Montero LópezSantiago Rodríguez López
Sep 22, 2011·Journal of Agricultural and Food Chemistry·Yu-Kuo ChenChung S Yang
Mar 30, 2012·BMC Public Health·Hui ZuoAkhtar Hussain
Oct 3, 2013·PloS One·Mohamed Abu-FarhaMohammed Dehbi
May 16, 2012·Diabetes·Jingyun YangJinying Zhao
Jan 1, 2014·International Scholarly Research Notices·Valmore BermúdezJosé López-Miranda
Sep 28, 2010·Metabolism: Clinical and Experimental·Ashraf S GorgeyDavid R Gater
Jul 26, 2013·Thrombosis and Haemostasis·Mariangela MorelliAmalia Gastaldelli
Jul 27, 2015·Current Diabetes Reports·Barry M Popkin
Nov 1, 2011·Progress in Neuro-psychopharmacology & Biological Psychiatry·Chin ChengTsuo-Hung Lan
Mar 28, 2012·Journal of Aging and Health·Martin SénéchalMartin Brochu
Jul 18, 2012·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Dae Yun SeoJin Han
Oct 27, 2016·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J ChenX Wang
Mar 7, 2017·Scientific Reports·Kendra L PuigColin K Combs
Aug 16, 2013·European Journal of Endocrinology·Silvia PelliteroManel Puig-Domingo
Jan 18, 2014·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Anne S GramElse-M Bladbjerg
Nov 9, 2016·Nutrition & Metabolism·Mélany PierardAlexandre Legrand
May 1, 2012·Expert Review of Endocrinology & Metabolism·Anne Q ReuwerVincent Goffin
Jan 6, 2021·International Journal of Molecular Sciences·Florian JuszczakAnne-Emilie Declèves
Dec 22, 2020·Frontiers in Sports and Active Living·Camilla M MandrupBente Stallknecht