Aberrant Cerebellar Resting-State Functional Connectivity Related to Reading Performance in Struggling Readers.

Developmental Science
Brian GreeleyLara A Boyd

Abstract

Reading is a critical neurodevelopmental skill for school-aged children, which requires a distributed network of brain regions including the cerebellum. However, we do not know how functional connectivity between the cerebellum and other brain regions contributes to reading. Here we used resting-state functional connectivity to understand the cerebellum's role in decoding, reading speed, and comprehension in a group of struggling readers (RD) and a group of adolescents and children with typical reading abilities (TD). We observed an increase in functional connectivity between the sensorimotor network and the left angular gyrus, left lateral occipital cortex, and right inferior frontal gyrus in the RD group relative to the TD group. Additionally, functional connectivity between the cerebellum network and the precentral gyrus was decreased and was related to reading fluency in the RD group. Seed-based analysis revealed increased functional connectivity between crus 1, lobule 6, and lobule 8 of the cerebellum and brain regions related to the default mode network and the motor system for the RD group. We also found associations between reading performance and the functional connectivity between lobule 8 of the cerebellum and the le...Continue Reading

References

Apr 1, 1996·Optometry and Vision Science : Official Publication of the American Academy of Optometry·M T Kulp, P P Schmidt
Jul 22, 1998·Proceedings of the National Academy of Sciences of the United States of America·B HorwitzB C Donohue
Aug 17, 2001·Trends in Neurosciences·R I NicolsonP Dean
Jan 18, 2002·Experimental Brain Research·Heidi Johansen-Berg, P M Matthews
Mar 6, 2002·Journal of Neurophysiology·Catherine E Lang, Amy J Bastian
Apr 5, 2002·Neuropsychologia·Caroline RaeJohn F Stein
Aug 23, 2002·Journal of Cognitive Neuroscience·Klaus MathiakHermann Ackermann
Dec 31, 2002·Proceedings of the National Academy of Sciences of the United States of America·Michael D GreiciusVinod Menon
Jan 23, 2003·Brain : a Journal of Neurology·Mark A EckertVirginia W Berninger
Mar 30, 2004·The Journal of Physiology·Zafiris J DaskalakisRobert Chen
Oct 16, 2004·Human Brain Mapping·Andreas JansenStefan Knecht
Oct 23, 2004·Journal of Learning Disabilities·A J FawcettF Maclagan
Apr 13, 2006·Developmental Medicine and Child Neurology·Helena ViholainenHeikki Lyytinen
Aug 24, 2006·Cerebral Cortex·Jan KujalaRiitta Salmelin
Jul 14, 2007·Folia Phoniatrica Et Logopaedica : Official Organ of the International Association of Logopedics and Phoniatrics (IALP)·Filippos VlachosGeorgia Andreou
Apr 11, 2008·Annals of the New York Academy of Sciences·Randy L BucknerDaniel L Schacter
Nov 7, 2008·Brain and Language·Hanne BaillieuxPeter Mariën
Jan 12, 2010·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Catherine J Stoodley, John F Stein
Jun 1, 2010·Brain Structure & Function·Vinod Menon, Lucina Q Uddin
Dec 22, 2010·Proceedings of the National Academy of Sciences of the United States of America·Fumiko HoeftJohn D E Gabrieli
Mar 4, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Robert LeechDavid J Sharp
May 31, 2012·Brain Connectivity·Susan Whitfield-Gabrieli, Alfonso Nieto-Castanon
Dec 1, 2012·Brain : a Journal of Neurology·Carl D HackerAbraham Z Snyder
Jan 22, 2013·Neuroscience and Biobehavioral Reviews·Luiz Kobuti Ferreira, Geraldo F Busatto
May 14, 2014·Physics of Life Reviews·Luiz Pessoa
Jan 1, 2013·Brain Sciences·Karen E WaldieIan J Kirk
Aug 30, 2014·Cerebral Cortex·Matthias SchurzMartin Kronbichler
Aug 25, 2015·Developmental Cognitive Neuroscience·Zhen YangMichael P Milham
Aug 24, 2016·Cerebral Cortex·Lucy R ChaiDanielle S Bassett
Feb 1, 2017·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Danny A SpampinatoPablo A Celnik
Aug 19, 2017·Brain and Language·C Nikki ArringtonJack M Fletcher

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.