Aberrant serum adiponectin levels in women with uterine leiomyomas

Gynecologic and Obstetric Investigation
Hung-Sheng ChenShyng-Shiou F Yuan

Abstract

Adiponectin is an adipocyte-secreted hormone. Serum adiponectin levels are inversely correlated with insulin resistance, and low plasma adiponectin levels have been demonstrated in type 2 diabetic patients. However, information on serum adiponectin levels in gynecological disorders is mostly lacking. In this study, we analyzed the possible correlation between serum adiponectin levels and uterine leiomyomas. Serum adiponectin levels, determined by radioimmunoassay, were compared in women with uterine leiomyomas (n = 47) and normal controls (n = 46). Serum adiponectin levels in women with uterine leiomyomas (16.4 +/- 0.9 microg/ml) were significantly lower (p < 0.05) than those in the normal controls (19.5 +/- 1.0 microg/ml). Furthermore, there was an inverse correlation between serum adiponectin levels and body mass index, in both women with leiomyomas and normal controls. Serum adiponectin levels are significantly decreased in myomatous patients.

References

Feb 1, 1988·The Journal of Clinical Endocrinology and Metabolism·A M SuikkariM Seppälä
Jan 1, 1989·The Journal of Clinical Endocrinology and Metabolism·A M SuikkariH Yki-Järvinen
May 1, 1987·Annals of Clinical Biochemistry·O SadanM Robinson
Jun 1, 1995·American Journal of Obstetrics and Gynecology·E Y StrawnC L Bethea
Nov 1, 1994·International Journal of Cancer. Journal International Du Cancer·L T van der VenW den Otter
Apr 1, 1994·Obstetrics and Gynecology·L S WilcoxH B Peterson
Mar 27, 1999·Biochemical and Biophysical Research Communications·Y AritaY Matsuzawa
Jun 10, 2000·Arteriosclerosis, Thrombosis, and Vascular Biology·K HottaY Matsuzawa
Oct 19, 2000·Environmental Health Perspectives·A F Haney
Aug 2, 2001·Nature Medicine·A H BergP E Scherer
Feb 21, 2002·Trends in Endocrinology and Metabolism : TEM·Anders H BergPhilipp E Scherer
Oct 5, 2002·The Journal of Clinical Endocrinology and Metabolism·Nicola AbateScott M Grundy
Mar 22, 2003·Acta Obstetricia Et Gynecologica Scandinavica·Te-Fu ChanShyng-Shiou F Yuan

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Citations

May 25, 2016·Current Obstetrics and Gynecology Reports·Nick Dalton-Brewer
Jun 15, 2007·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Marta ArchancoMaría A Burrell
Dec 29, 2012·Reproductive Sciences·George AngelidisIoannis E Messinis
May 28, 2010·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Atsuko WakabayashiTadashi Kimura
Aug 2, 2005·Human Reproduction·Yuri TakemuraYuji Taketani
Nov 23, 2019·Obstetrical & Gynecological Survey·Abdelrahman AlAshqarMostafa A Borahay
Jan 4, 2020·Therapeutic Advances in Endocrinology and Metabolism·Chin-Hsiao Tseng
Mar 20, 2021·Biology of Reproduction·Abdelrahman AlAshqarMostafa A Borahay

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