Ability of blue laser imaging with magnifying endoscopy for the diagnosis of gastric intestinal metaplasia

Lasers in Medical Science
Honglei ChenChujun Li

Abstract

We aimed to determine the utility of blue laser imaging (BLI) with magnifying endoscopy (BLI-ME) for the prediction and diagnosis of gastric intestinal metaplasia (GIM). Participants, aged between 40 and 75 years, undergoing gastroscopy from January to April 2017 were included in this study. The ability of BLI-ME and white light endoscopy (WLE) to detect GIM was assessed by comparing the endoscopic findings with the histological findings. The correlation between the grades of light blue crest (LBC) appearance and histology grade of GIM was calculated. We included 100 participants in this study. GIM was diagnosed in 27 participants; 20 participants were detected by both BLI and WLE, four by BLI only, and three exclusively by random biopsies. The values of sensitivity, specificity, positive predictive values, and negative predictive values for detecting GIM were 34.9, 38.9, 25.4, and 57.1%, respectively, for WLE and 88.9, 96.7, 94.1, and 93.3%, respectively, for BLI-ME. The diagnostic accuracy for GIM was 43% for WLE and 94.0% for BLI-ME. A good correlation between the grades of LBC and the grades of GIM on histology was observed (P < 0.01). BLI-ME achieved a good diagnostic efficiency for detection of GIM. LBC seen on BLI-ME is ...Continue Reading

References

Apr 16, 2010·Digestive Diseases and Sciences·Lisette G CapelleErnst J Kuipers
May 16, 2013·World Journal of Gastroenterology : WJG·Edoardo SavarinoVincenzo Savarino
Jun 5, 2013·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Naohisa YoshidaYuji Naito
Jul 9, 2014·Current Opinion in Gastroenterology·Veroushka Ballester, Marcia Cruz-Correa
Jan 21, 2015·The American Journal of Surgical Pathology·Robert M Genta, Amnon Sonnenberg
Jul 3, 2015·Endoscopy International Open·Kazuhiro KanekoShogo Nomura
Jun 14, 2016·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Osamu DohiYoshito Itoh
Oct 16, 2016·Gastroenterology Research and Practice·Akira TomieYoshito Itoh
Nov 11, 2016·Journal of Cancer Research and Clinical Oncology·Jian-Xia JiangShun-Fu Xu
Dec 13, 2016·Best Practice & Research. Clinical Gastroenterology·Jorge LageKenshi Yao
Dec 9, 2017·BMC Gastroenterology·Yoshikazu YoshifukuKazuaki Chayama

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Citations

Nov 6, 2018·Clinical Endoscopy·Hiroyuki OsawaHironori Yamamoto
Aug 16, 2019·Current Opinion in Gastroenterology·David Y GrahamRobert M Genta
Feb 27, 2019·Journal of Clinical Gastroenterology·Michael Peng, Douglas K Rex
Nov 5, 2019·Scandinavian Journal of Gastroenterology·Rui CastroMário Dinis-Ribeiro
Jul 21, 2020·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Jingyuan ZhouAiqun Liu
Jan 30, 2021·Clinical and Translational Gastroenterology·Nicolas ChapelleTamara Matysiak-Budnik
Jul 18, 2020·European Journal of Gastroenterology & Hepatology·Ning WeiRui Hua Shi

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