Ability of salivary biomarkers in the prognostic of systemic and buccal inflammation

Journal of Clinical and Experimental Dentistry
Aida Gutiérrez-CorralesJosé-Luis Gutiérrez-Pérez

Abstract

Nowadays, there is a growing interest in using saliva as an alternative sample for the diagnosis, prediction and progression of several diseases. It has been established that some molecules found in saliva are related to oral inflammatory processes and systemic health status. Furthermore, it is known that saliva is crucial for the carrying out of different functions in the oral cavity and its role in the local modulation of inflammatory and immune response is being thoroughly studied by the health research community. The aim of this review is to analyze the most important biomarkers which have been utilized in biomedicine during the last two decades in order to establish a correlation between certain specific salivary biomarkers and systemic inflammation. Then, we discuss the utility of total proteins, immunoglobulin A and alpha-amylase as biomarkers for the prognostic of local inflammation after oral surgery. Key words:Inflammation, salivary biomarkers, systemic disease, buccal surgery, total proteins, inmunoglobulin A, Alpha-amylase.

Citations

Jun 12, 2018·BioMed Research International·Farah Asa'adGiovanni Damiani
Dec 18, 2021·Frontiers in Physiology·Roxane MonnoyerIngrid Eftedal

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Methods Mentioned

BETA
flow cytometry
ELISA

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