Abstract
This investigation details our experience using a loop catheter to ablate atrial fibrillation (AF) in dogs. Atrial fibrillation is the most common arrhythmia and has significant morbidity. Maintenance of normal sinus rhythm (NSR) after conversion in many patients is still a challenge. A multi-electrode loop catheter was used to create linear atrial lesions to ablate AF in a rapid atrial pacing model in 29 dogs. Rhythm status was assessed over a six-month recovery period, after which tissue analysis was performed. Acute conversion to NSR or atrial tachycardia (AT) was achieved in 90% of cases. Six of 26 conversions occurred after only left atrial (LA) lesions, and two after just right atrial lesions. Sixteen (62%) of 26 lesions that resulted in AF conversion were in the LA, and 11 of these 16 conversions occurred during a lesion connecting the mitral ring to the pulmonary veins. Acute conversion rate was similar with ring and coil electrodes, but AT was more frequent with coil electrodes (63% vs. 31%). At six months 80% of dogs were in NSR, 14% were in AT, and 7% remained in AF. There was an average reduction in P-wave amplitude of 64 +/- 26% after power application. Tissue analysis revealed transmural contiguous lesions when fi...Continue Reading
References
Apr 1, 1979·American Heart Journal·E L MichelsonH MacVaugh
Apr 15, 1995·Circulation·A ElvanD P Zipes
Mar 1, 1995·Circulation·C A MorilloC M Guiraudon
Oct 1, 1993·The Annals of Thoracic Surgery·J L CoxD G Lappas
Nov 1, 1995·Archives of Disease in Childhood·J V De Giovanni
Dec 1, 1996·Journal of Cardiovascular Electrophysiology·M HaïssaguerreJ Clémenty
Feb 4, 1997·Circulation·P JaïsJ Clémenty
Jun 3, 1997·Circulation·C W ChiouD P Zipes
Oct 7, 1997·Circulation·A ElvanD P Zipes
Nov 14, 1997·Circulation·J E OlginM D Lesh
Dec 24, 1997·Circulation·I D McRuryD E Haines
Apr 16, 1998·Circulation·M A MitchellD E Haines
Sep 3, 1998·The New England Journal of Medicine·M HaïssaguerreJ Clémenty
Jan 20, 1999·Circulation·D ShahJ Clémenty
Mar 26, 1999·Journal of the American College of Cardiology·B AvitallG N Gupta
Citations
Feb 7, 2012·Journal of Cardiovascular Medicine·Sen LeiYu Hou
Aug 17, 2006·Journal of Cardiovascular Electrophysiology·Thomas RostockMichel Haïssaguerre
Feb 6, 2017·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Boaz AvitallJosef Koblish
May 28, 2019·Pacing and Clinical Electrophysiology : PACE·Kennosuke YamashitaRavi Ranjan
Jan 8, 2005·European Heart Journal·Thomas J van BrakelJos G Maessen
Jul 3, 2013·American Journal of Physiology. Heart and Circulatory Physiology·Derek J DosdallNassir F Marrouche