PMID: 9557758Apr 29, 1998Paper

Ablation of teflon granuloma with the free-electron laser emitting in the eight- to nine-micron range

The Annals of Otology, Rhinology, and Laryngology
G L BryantJ A Werkhaven

Abstract

In this study, we developed a rat model for Teflon granuloma and used this model to evaluate the removal of the granuloma at laser wavelengths at which Teflon has a maximal absorption. Twenty-four Teflon granulomas were created in 12 rats, and the gross and histologic effects from laser incision at four different wavelengths (8.25, 8.5, 8.75, and 10.6 microm) were evaluated acutely and at 7 and 14 days postoperatively. Polytetrafluoroethylene, or Teflon, is a relatively inert substance that has been used over the past 4 decades for endoscopic injection into the thyroarytenoid muscle of the larynx for the purposes of laryngeal rehabilitation in cases of unilateral vocal fold paralysis or incomplete glottic closure. In certain cases in which formation of granulomatous reaction to the Teflon occurs, patients may have significant dysphonia or airway compromise. Once Teflon has infiltrated the surrounding tissue planes, it is exceedingly difficult to remove endoscopically. Endoscopic removal of this granuloma is usually attempted with the carbon dioxide (CO2) laser and has had limited success. Examination of the infrared absorption spectrum of polytetrafluoroethylene reveals strong absorption in the mid-infrared region in the 8- to ...Continue Reading

References

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Citations

Sep 16, 2004·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Ming-Wang Hsiung, Yu-Liang Lin
Apr 6, 2004·Otolaryngologic Clinics of North America·Mark S Courey
Sep 28, 1998·The Annals of Otology, Rhinology, and Laryngology·J L NettervilleR H Ossoff
Apr 1, 2004·The Annals of Otology, Rhinology, and Laryngology·Manuel Bernal-SprekelsenLlucia Alòs
Feb 4, 1999·The Annals of Otology, Rhinology, and Laryngology·C F LanoJ A Werkhaven
Jul 27, 2001·Journal of Biomaterials Science. Polymer Edition·G C XuK Awazu

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