Abnormal asymmetry of N200 and P300 event-related potentials in subclinical depression

Journal of Affective Disorders
Alexander L SumichMichael Brammer

Abstract

Sex differences for depression in prevalence and symptom profile may in part be due to differences between men and women in brain dysfunction associated with the disorder. Changes in event-related potential (ERP) measures similar to those seen in clinical populations are reported in subclinical or premorbid forms of depression. The current study investigates sex differences in ERPs associated with subclinical depression. One-hundred-and-forty healthy, right-handed adults (aged 20-60 years; screened to exclude clinical depression and psychosis) completed an auditory oddball task and the Depression Anxiety and Stress Scale (DASS). Seventy (n = 35 men) subclinically depressed (SD) (i.e. scoring >2 for depression on DASS) participants were matched for age and education with 70 (n = 35 men) participants showing no signs of depression (ND). Repeated measures multivariate analysis of variance was used to test for differences in N200 and P300 amplitude between SD and ND groups. ND, but not SD groups had asymmetry (R > L) of central N200 amplitude. Similar asymmetry was seen in ND, but not SD men at posterior sites. SD groups demonstrated left > right posterior P300 amplitude asymmetry due to P300 enhancement at left temporoparietal sit...Continue Reading

References

Dec 1, 1992·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·C Shagass, R A Roemer
Dec 1, 1992·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·C Shagass, R A Roemer
Jan 1, 1990·Schizophrenia Bulletin·R C JosiassenC Shagass
Nov 1, 1993·Psychophysiology·J E Giese-DavisR A Knight
Jul 1, 1996·The International Journal of Neuroscience·J F DefranceJ C Sharma
Nov 4, 1996·Neuroreport·F el MassiouiD Widlöcher
Nov 14, 1997·Neuroreport·R LarishH W Mueller-Gaertner
Aug 5, 1999·Psychophysiology·L O FernandesG A Miller
Mar 31, 2000·Journal of Abnormal Psychology·P J DeldinG A Miller
Jul 7, 2000·Psychological Medicine·A PiersonM Leboyer
Apr 26, 2001·Journal of Clinical and Experimental Neuropsychology·M Liotti, H S Mayberg
Jun 5, 2001·Journal of Cognitive Neuroscience·D L Woods, C Alain
Sep 14, 2001·Psychiatry and Clinical Neurosciences·M R MannanH Ohta
Jun 6, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Rita CeponieneRisto Näätänen
Jun 14, 2002·Journal of Affective Disorders·Jane M MurphyAlexander H Leighton
Jul 2, 2002·The American Journal of Psychiatry·Thomas FrodlHans-Jürgen Möller
Aug 2, 2002·Archives of General Psychiatry·William G IaconoMatthew McGue
Aug 24, 2002·Clinical EEG (electroencephalography)·Gerard E BruderFrederic M Quitkin
Jan 18, 2003·Sleep Medicine Reviews·Roseanne Armitage, Robert F. Hoffmann
Mar 27, 2003·The Australian and New Zealand Journal of Psychiatry·David M Clarke, Dean P McKenzie
Jun 28, 2003·The British Journal of Clinical Psychology·John R Crawford, Julie D Henry
Dec 23, 2003·Progress in Neuro-psychopharmacology & Biological Psychiatry·Enrique BacaAlberto Porras-Chavarino
Feb 3, 2004·The American Journal of Psychiatry·Tamar WohlfarthWim van den Brink
Jul 9, 2004·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Gerard E BruderFrederic M Quitkin
Nov 17, 2005·The International Journal of Neuroscience·L M WilliamsE Gordon
Jun 30, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Alex SumichLeanne M Williams

❮ Previous
Next ❯

Citations

Jul 18, 2012·Developmental Neuropsychology·Alexander L SumichKatya Rubia
Jun 5, 2012·Trends in Neurosciences·C M SylvesterE J Lenze
Dec 23, 2008·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Dong GaoXueli Sun
Jun 30, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Alex SumichLeanne M Williams
Apr 15, 2015·International Journal of Obesity : Journal of the International Association for the Study of Obesity·S ReyesC Algarin
Dec 25, 2012·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·D B SpronkR J Verkes
Dec 3, 2014·Journal of Affective Disorders·E GreimelG Schulte-Körne
May 23, 2014·Journal of Clinical and Experimental Neuropsychology·Yanqi Ryan LiMurray T Maybery
Jan 15, 2019·Nordic Journal of Psychiatry·Lina ZhouHanping Bai
Feb 5, 2021·Psychophysiology·Lucas De ZorziHenrique Sequeira

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.