Abnormal blood oxygen level-dependent fluctuations and remote connectivity in sleep-related hypermotor epilepsy.

Acta Neurologica Scandinavica
Wenyu LiuDong Zhou

Abstract

Sleep-related hypermotor epilepsy (SHE) is a form of the epileptic syndrome that involves stereotyped hypermotor seizures and presents as asymmetric tonic or dystonic posturing events. We aimed to investigate the brain activities of SHE patients using structural and functional magnetic resonance imaging (fMRI). A total of 41 patients with SHE and 41 age- and sex-matched healthy controls (HCs) were prospectively enrolled and assessed using fMRI. The two groups were compared in amplitude of low-frequency fluctuations (ALFF) and regional homogeneity (ReHo), and potential correlations between these measures and clinical features were also examined. The involvement of functional network integration was explored by analyzing seed-based functional connectivity. In SHE patients, ALFF in the right precentral gyrus was significantly higher than in HCs, and ReHo in the left postcentral and right precentral gyrus was higher. None of the brain regions had lower ALFF or ReHo compared to HCs. ReHo in the left postcentral gyrus and ALFF in the right precentral gyrus were both negatively correlated with epilepsy duration. Patients with SHE had higher functional connectivity mainly in the precuneus, postcentral gyrus, and supplementary motor are...Continue Reading

References

Oct 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·B BiswalJ S Hyde
Jun 4, 1999·Brain : a Journal of Neurology·F ProviniP Montagna
Feb 13, 2001·Journal of Neurology, Neurosurgery, and Psychiatry·A BirabenP Chauvel
Jan 18, 2003·Sleep Medicine Reviews·Federica ProviniElio Lugaresi
Jan 10, 2006·Brain : a Journal of Neurology·Andrea E Cavanna, Michael R Trimble
Jul 4, 2006·Brain : a Journal of Neurology·F PicardM Bottlaender
Oct 5, 2012·Annals of Neurology·Davinia Fernández-EspejoAdrian M Owen
Nov 11, 2014·NeuroImage. Clinical·Megan L McGillThomas Thesen
Dec 20, 2014·Computational and Mathematical Methods in Medicine·Xinzhi CaoGuangming Lu
Jan 8, 2015·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Allison C NugentWilliam H Theodore
Jul 15, 2015·Sleep Medicine Reviews·Steve A GibbsLino Nobili
Nov 6, 2015·Brain Connectivity·Mangor PedersenGraeme Jackson
May 11, 2016·Neurology·Paolo TinuperRuth Ottman
Aug 31, 2016·The International Journal of Neuroscience·Fangfang XieWei Shi
Oct 16, 2016·Human Brain Mapping·Samantha I CunninghamNora D Volkow
Mar 13, 2018·NeuroImage. Clinical·Stefania EvangelistiRaffaele Lodi
Sep 27, 2018·Brain Topography·Benjamin Klugah-BrownDezhong Yao
Apr 27, 2019·BMC Neurology·Benjamin Klugah-BrownDezhong Yao

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Citations

Feb 27, 2021·Seizure : the Journal of the British Epilepsy Association·Wenyu LiuXintong Wu

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