Abnormal cortical activation during planning of voluntary movement in patients with epilepsy with focal motor seizures: event-related desynchronization study of electroencephalographic mu rhythm

Epilepsia
Philippe DerambureJ D Guieu

Abstract

The spatiotemporal distribution of EEG mu rhythm desynchronization was analyzed in patients with partial epilepsy to determine whether frequent focal motor seizures could induce a change of cortical activation during the planning of a voluntary movement. The event-related desynchronization (ERD) of the mu rhythm was quantified during a self-paced voluntary movement of the thumb. The results were compared between two groups of patients with epilepsy: in one group (n = 12), the patients had frontal lobe epilepsy with frequent focal motor seizures (FMS); in the second group (n = 12), they had temporal lobe epilepsy (TLE) with complex partial seizures but no ictal movement disorder. The results were also compared with those of control subjects of same age (n = 10). In the control group, desynchronization of mu rhythm began over the contralateral central region 2,000 ms before the movement onset. In the FMS group, the desynchronization of mu rhythm was delayed, appearing only 500 ms before the movement onset, and the amplitude of ERD was increased over the frontocentral region. In the TLE group, the spatiotemporal pattern of ERD was the same as in normal subjects, but the amplitude of ERD was increased. These results indicate that t...Continue Reading

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Citations

Dec 16, 2003·Neurophysiologie clinique = Clinical neurophysiology·D DevosL Defebvre
May 29, 2004·Neurobiology of Aging·E LabytP Derambure
Nov 9, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·F CassimJ Guieu
Oct 30, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·B TurakM Lamarche
Jan 22, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·B GraimannG Pfurtscheller
Dec 24, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·William SzurhajFrançois Mauguière
Jun 14, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·E LabytPh Derambure
Dec 4, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·E LabytP Derambure
Nov 27, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·G Pfurtscheller, F H Lopes da Silva
Dec 6, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·E HoudayerP Derambure
May 20, 2008·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Stefanie HellwigStephan Bender
Apr 9, 2005·The European Journal of Neuroscience·William SzurhajPhilippe Derambure
Jul 21, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Stephan BenderRieke Oelkers-Ax
Aug 5, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·E LabytP Derambure
Jun 26, 2020·Frontiers in Neurology·Nathalie GernerYvonne Höller

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