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Abnormal DNA patterns in animal mitochondria: ethidium bromide-induced breakdown of closed circular DNA and conditions leading to oligomer accumulation

Proceedings of the National Academy of Sciences of the United States of America

Dec 1, 1970

M M Nass

PMID: 4321352

Abstract

Treatment of cultured mouse fibroblasts (L-cells) and hamster kidney cells with ethidium bromide was found to inhibit the incorporation of [(3)H]thymidine into mitochondrial closed-circular DNA, but not into nuclear DNA. The specific activity of nuclear DNA in treated cells was higher t...read more

Mentioned in this Paper

Centrifugation, Density Gradient
Vinblastine
Specimen Type - Fibroblasts
Depression, Chemical
Thymidine
DNA, Mitochondrial
DNA, Viral
Mengovirus
Hamsters
Kidney
Paper Details
References
  • References14
  • Citations70
12
  • References14
  • Citations70
12345...

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Abnormal DNA patterns in animal mitochondria: ethidium bromide-induced breakdown of closed circular DNA and conditions leading to oligomer accumulation

Proceedings of the National Academy of Sciences of the United States of America

Dec 1, 1970

M M Nass

PMID: 4321352

DOI:

Abstract

Treatment of cultured mouse fibroblasts (L-cells) and hamster kidney cells with ethidium bromide was found to inhibit the incorporation of [(3)H]thymidine into mitochondrial closed-circular DNA, but not into nuclear DNA. The specific activity of nuclear DNA in treated cells was higher t...read more

Mentioned in this Paper

Centrifugation, Density Gradient
Vinblastine
Specimen Type - Fibroblasts
Depression, Chemical
Thymidine
DNA, Mitochondrial
DNA, Viral
Mengovirus
Hamsters
Kidney

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BK Virus Infection

BK virus infection is a significant complication of modern immunosuppression used in kidney transplantation. Discover the latest research on BK virus infection here.

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Proceedings of the National Academy of Sciences of the United States of America

Circular oligomers in mitochondrial DNA of human and beef nonmalignant thyroid glands

Proceedings of the National Academy of Sciences of the United States of AmericaApril 1, 1972
C PaolettiJ Pairault
Paper Details
References
  • References14
  • Citations70
12
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12345...
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