Abnormal exploratory eye movements in schizophrenic patients vs healthy subjects

Acta Neurologica Scandinavica
H RyuH Maeda

Abstract

We examined previously described exploratory eye movements abnormalities as biologic markers in schizophrenic patients in comparison with age-matched healthy subjects. Using an eye-mark recorder, eye movements were analysed for mean gazing time, total number of gazing points, mean eye scanning length, total eye scanning length, and total gazing times as subjects viewed six simple pictures in preparation for copying them. In-patients, and to a lesser extent, out-patients, with schizophrenia showed a longer gazing time, fewer gazing points, a shorter mean and total eye scanning length. and longer gazing time than healthy subjects. In schizophrenic patients. negative symptom scores were positively correlated with mean gazing time (r = 0.33), and negatively correlated with the total number of gazing points (r = -0.29) as well as, the mean (r = -0.40) and total scanning length (r = -0.46). Exploratory eye movements are a biologic marker useful for evaluation of schizophrenia.

References

Jul 1, 1977·Archives of General Psychiatry·P S HolzmanN J Yasillo
Jan 1, 1992·Schizophrenia Bulletin·T KojimaY Shimazono
Jul 1, 1990·Psychological Bulletin·B A Clementz, J A Sweeney
May 1, 1990·Biological Psychiatry·T KojimaY Shimazono
Jan 1, 1972·Folia Psychiatrica Et Neurologica Japonica·H MoriyaR Ogiwara
Jul 13, 1973·Science·P S HolzmanD W Hughes
Feb 1, 1984·Archives of General Psychiatry·P S HolzmanC S Waternaux
Feb 24, 2001·Life Sciences·A MiyahiraH Maeda
Jan 1, 1962·Archives of General Psychiatry·D SHAKOW
Nov 1, 1962·British Journal of Psychology·E C POULTON
Nov 24, 2004·Psychiatry and Clinical Neurosciences·A MiyahiraH Maeda

❮ Previous
Next ❯

Citations

Apr 23, 2013·Lancet Neurology·Raja Mehanna, Joseph Jankovic
May 5, 2005·Journal of Abnormal Psychology·Rebecca L FullerJames M Gold
Apr 2, 2003·Psychiatry and Clinical Neurosciences·Hironobu NakayamaHisao Maeda
Sep 17, 2013·PloS One·Simon SchwabAndreas Altorfer
Jan 13, 2011·Journal of Psychiatry & Neuroscience : JPN·Sara A BeedieDavid M St Clair
Feb 9, 2012·Brain & Development·Yukihiko KonishiYukuo Konishi
Jul 25, 2006·Schizophrenia Research·Patricia E G BestelmeyerDavid St Clair
May 7, 2011·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Sara A BeedieDavid M St Clair
Jun 17, 2016·European Archives of Psychiatry and Clinical Neuroscience·Alexandra NikolaidesStephan Ruhrmann
Dec 14, 2004·European Psychiatry : the Journal of the Association of European Psychiatrists·Tomasz Kleszczewski, Wiesław Rutkiewicz
Jun 29, 2021·Frontiers in Behavioral Neuroscience·Fotios AthanasopoulosNikolaos Smyrnis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.