Abnormal FDG and MIBG Activity in the Bones in a Patient With Neuroblastoma Without Detectable Primary Tumor

Clinical Nuclear Medicine
Wei ZhangSabah Servaes

Abstract

Neuroblastoma is among the most common extracranial solid tumors in pediatric patients and typically arises anywhere from the neck to pelvis but most commonly in the adrenal glands. It is extremely rare for a patient to have extensive metastases from neuroblastoma without primary tumor being identified. We present a 3-year-old with widespread bone and bone marrow involvement of the disease revealed on both FDG PET/CT and MIBG scan, which was pathologically proven as neuroblastoma. However, extensive imaging did not detect primary tumor anywhere.

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Citations

Feb 7, 2017·Clinical Nuclear Medicine·Kun Zheng, Hongming Zhuang
Jan 3, 2019·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Nino RainussoHeidi V Russell
Jun 27, 2017·Clinical Nuclear Medicine·Yin Jie ChenHongming Zhuang
Jun 21, 2017·Clinical Nuclear Medicine·Wei Zhang, Hongming Zhuang
Oct 7, 2020·Medicine·Can HuangJingwei Yang

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