Abnormal functional connectivity density in sleep-deprived subjects

Brain Imaging and Behavior
Liu YangZheng Yang

Abstract

Sleep deprivation (SD) can alter the intrinsic brain functional organization. However, its effects on intrinsic low-frequency connectivity in the whole brain have not been well characterized. In this study, we used voxel-based functional connectivity density (FCD) analysis to investigate the effects of SD on the spontaneous functional organization of the brain. Thirty-seven healthy participants underwent this within-subject crossover functional magnetic resonance imaging (fMRI) study during rested wakefulness (RW) and after 36 h of total sleep deprivation (TSD). Decreased long-/short-range FCDs were observed in the posterior cingulate cortex, precuneus, inferior parietal lobule, dorsolateral prefrontal cortex, dorsomedial prefrontal cortex, and ventromedial prefrontal cortex. Increased long-/short-range FCDs were found in the sensory integration and arousal regulating areas, including the postcentral gyrus, thalamus, superior temporal gyrus, and occipital-temporal cortex. Moreover, a significant negative correlation was found between the short-range FCD of the PCC and the reaction time of Psychomotor Vigilance Task. In the present study, spontaneous functional organization with significant group-wise differences between RW and ...Continue Reading

References

Feb 24, 2001·Proceedings of the National Academy of Sciences of the United States of America·M E RaichleG L Shulman
Jun 29, 2005·NeuroImage·Brian Nils LundstromKarl Magnus Petersson
Jul 11, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Y M Lisa ChuahMichael W L Chee
Sep 21, 2006·Brain : a Journal of Neurology·Foucaud du BoisgueheneucBruno Dubois
May 17, 2008·Cerebral Cortex·D TomasiN D Volkow
Sep 19, 2009·NeuroImage·Michael W L CheeVitali Zagorodnov
May 12, 2010·Proceedings of the National Academy of Sciences of the United States of America·Dardo Tomasi, Nora D Volkow
May 18, 2010·Magma·Philipp G SämannMichael Czisch
Feb 2, 2011·Cerebral Cortex·Dardo Tomasi, Nora D Volkow
Mar 23, 2011·Human Brain Mapping·Dardo Tomasi, Nora D Volkow
May 26, 2011·NeuroImage·Dardo Tomasi, Nora D Volkow
Sep 1, 2011·Cerebral Cortex·Dardo Tomasi, Nora D Volkow
Dec 14, 2011·Biological Psychiatry·Dardo Tomasi, Nora D Volkow
May 18, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mareike M MenzJan Peters
Jun 6, 2012·Molecular Psychiatry·C SchillingUNKNOWN IMAGEN consortium (www.imagen-europe.com)
Jan 17, 2014·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Amanda V UtevskyScott A Huettel
Jan 29, 2014·NeuroImage·Danyang KongMichael W L Chee
Mar 20, 2014·Cerebral Cortex·Wen QinChunshui Yu
Mar 29, 2014·Journal of Sleep Research·Huan LiuXu Lei
Aug 15, 2014·Neuroscience and Biobehavioral Reviews·Markus H Schmidt
Mar 19, 2015·Frontiers in Systems Neuroscience·Shruti JapeeLeslie G Ungerleider
Apr 1, 2015·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Marcus E Raichle
Sep 25, 2015·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Eti Ben SimonTalma Hendler
Oct 13, 2015·Neurobiology of Learning and Memory·Céline CharroudTasnime N Akbaraly
Apr 4, 2017·Human Brain Mapping·Eti Ben SimonTalma Hendler

❮ Previous
Next ❯

Citations

May 12, 2020·Frontiers in Neuroscience·Thomas T Liu, Maryam Falahpour
Dec 1, 2020·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Francesca MiragliaPaolo Maria Rossini

❮ Previous
Next ❯

Software Mentioned

3dFWHMx
3dClustSim
Analysis of Functional NeuroImages ( AFNI )
in
AFNI
Linux
house

Related Concepts

Related Feeds

Brain Imaging of Neural Circuits

Neural circuits are groups of interconnected neurons which carry out specific functions when activated. Imaging these neural circuits allows researches to further elucidate their mechanisms and functions. Follow this feed to stay up to date on brain imaging of neural circuits.

Brain Imaging of Neural Circuits (MDS)

Neural circuits are groups of interconnected neurons which carry out specific functions when activated. Imaging these neural circuits allows researches to further elucidate their mechanisms and functions. Follow this feed to stay up to date on brain imaging of neural circuits.