Abnormal glucose metabolism in Hispanic parents of children with acanthosis nigricans.

ISRN Endocrinology
Ximena Urrutia-RojasCraig Spellman

Abstract

Objective. Assess the prevalence of abnormal glucose metabolism among Hispanic parents of children with acanthosis nigricans (AN). Methods. Hispanic families (n = 258) were evaluated for metabolic and anthropometric parameters including fasting glucose levels and AN status. Results. Mothers with AN+ children had IFG (17.3%) and 4% had glucose levels ≥126 mg/dL (P = 0.028) compared to 7.1% and 1.8% of mothers with AN- children, respectively. Mothers of AN+ children also had greater odds of having impaired fasting glucose levels (OR: 3.917, 95% CI: 1.475-10.404; P < 0.004) but this was not the case for fathers (OR: 1.125, 95% CI: 0.489-2.586; P = 0.781). Mothers of AN+ children were also more likely to be AN+ (OR: 5.76, 95% CI: 2.98-11.13, P < 0.001). Screening discovered glucose levels >126 mg/dL in 9% of fathers with AN+ children. Conclusions. Hispanic mothers of AN+ children are at higher risk of carbohydrate metabolism abnormalities. AN in children can be a marker for prevention and delay programs aimed at identifying adults at risk for diabetes.

References

Feb 1, 1976·The American Journal of Cardiology·W B Kannel
Jan 29, 2002·Gynecologic Oncology·Tarek M Mekhail, Maurie Markman
Mar 15, 2002·The New England Journal of Medicine·Ranjana SinhaSonia Caprio
Dec 25, 2003·Diabetes Care·Robert S SherwinUNKNOWN National Institute of Diabetes and Digestive and Kidney Diseases
Mar 26, 2004·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Ximena Urrutia-RojasWalter McConathy
Jun 8, 2004·The Journal of Clinical Endocrinology and Metabolism·Svetlana Ten, Noel Maclaren
Jul 17, 2004·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Patrick LitonjuaPhilip Raskin
Jul 11, 2006·Current Atherosclerosis Reports·Jeffrey A Switzer, David C Hess
Aug 23, 2006·Clinical and Experimental Pharmacology & Physiology·Valerie Burke
Jan 18, 2007·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Peter D GluckmanAlan S Beedle
Mar 1, 2007·Diabetes Care·David M NathanUNKNOWN American Diabetes Association
Apr 12, 2007·Hormone Research·Katerina HarwoodJoan DiMartino-Nardi
Sep 9, 2008·Diabetic Medicine : a Journal of the British Diabetic Association·S Genuth

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