Abnormal-induced theta activity supports early directed-attention network deficits in progressive MCI

Neurobiology of Aging
Marie-Pierre DeiberP Giannakopoulos

Abstract

The electroencephalography (EEG) theta frequency band reacts to memory and selective attention paradigms. Global theta oscillatory activity includes a posterior phase-locked component related to stimulus processing and a frontal-induced component modulated by directed attention. To investigate the presence of early deficits in the directed attention-related network in elderly individuals with mild cognitive impairment (MCI), time-frequency analysis at baseline was used to assess global and induced theta oscillatory activity (4-6Hz) during n-back working memory tasks in 29 individuals with MCI and 24 elderly controls (EC). At 1-year follow-up, 13 MCI patients were still stable and 16 had progressed. Baseline task performance was similar in stable and progressive MCI cases. Induced theta activity at baseline was significantly reduced in progressive MCI as compared to EC and stable MCI in all n-back tasks, which were similar in terms of directed attention requirements. While performance is maintained, the decrease of induced theta activity suggests early deficits in the directed-attention network in progressive MCI, whereas this network is functionally preserved in stable MCI.

References

Mar 1, 1992·Journal of Gerontology·P Barberger-GateauR Salamon
Nov 1, 1991·Journal of Clinical Psychology·M Mitrushina, P Satz
Feb 1, 1989·Electroencephalography and Clinical Neurophysiology·F PerrinJ F Echallier
Oct 1, 1987·Journal of Clinical and Experimental Neuropsychology·N ButtersJ Wolfe
Jun 1, 1982·The British Journal of Psychiatry : the Journal of Mental Science·C P HughesR L Martin
Oct 1, 1981·Journal of Clinical Neuropsychology·R GardnerL Empting
Oct 1, 1994·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·T DemiralpE Başar
Apr 1, 1996·Electroencephalography and Clinical Neurophysiology·F BabiloniA Urbano
Jun 1, 1997·Brain and Language·A SchniderD F Benson
Oct 23, 1997·Science·J H Morrison, P R Hof
Mar 27, 1999·Brain : a Journal of Neurology·R J Perry, J R Hodges
Apr 20, 1999·Neuroreport·R IshiiM Takeda
May 14, 1999·Trends in Cognitive Sciences·C Tallon-Baudry, O Bertrand
Nov 9, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·C M KrauseH Hämäläinen
Dec 26, 2001·Archives of Neurology·R C PetersenB Winblad
Mar 8, 2002·Alzheimer Disease and Associated Disorders·Martin GrunwaldHerman-Josef Gertz
Apr 16, 2002·Seminars in Speech and Language·Nancy S FoldiLynn A Schaefer
May 8, 2002·The European Journal of Neuroscience·Ole Jensen, Claudia D Tesche
Sep 18, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·J M OlichneyV J Iragui
Feb 27, 2003·Acta Neurologica Scandinavica. Supplementum·Henrike WolfLars-Olof Wahlund
Aug 27, 2003·Neurology·C A LuisR Duara
Sep 1, 1955·Journal of Abnormal Psychology·J E DOPPELT, W L WALLACE
Dec 3, 2003·Brain : a Journal of Neurology·Hélène AmievaJulie D Henry
Apr 6, 2004·International Journal of Geriatric Psychiatry·Heather S Davis, Kenneth Rockwood
Aug 21, 2004·International Psychogeriatrics·Maddalena Bruscoli, Simon Lovestone
Jun 24, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Pascal MissonnierPanteleimon Giannakopoulos
Jul 13, 2005·Archives of Neurology·Ronald C Petersen, John C Morris
Dec 15, 2005·Neuropsychology·Elena K FestaWilliam C Heindel
Dec 27, 2005·Current Alzheimer Research·John Polich, Jody Corey-Bloom
Jan 13, 2006·Neurobiology of Aging·K van der HieleH A M Middelkoop
Aug 12, 2006·Dementia and Geriatric Cognitive Disorders·Pascal MissonnierPanteleimon Giannakopoulos

❮ Previous
Next ❯

Citations

Mar 11, 2010·Journal of Neural Transmission·Pascal MissonnierPanteleimon Giannakopoulos
Feb 11, 2014·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Brigitta TóthMárk Molnár
Nov 28, 2012·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Sara AurtenetxeFernando Maestú
Dec 14, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Alan GevinsAaron B Ilan
May 10, 2011·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Jeffrey L Cummings
Jun 7, 2015·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Ling WeiYuping Wang
Apr 12, 2016·Frontiers in Human Neuroscience·Pascal W M Van Gerven, Maria J S Guerreiro
Jan 11, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Mehran AhmadlouHojjat Adeli
Apr 4, 2015·Neurobiology of Aging·Amanda C MarshallNicolas Geeraert
Dec 29, 2015·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Soon-Cheol ChungBoseong Kim
Apr 9, 2014·Neuropsychologia·Bahar Güntekin, Erol Başar
Jun 1, 2016·Frontiers in Aging Neuroscience·Xiangfei HongShanbao Tong
Jun 4, 2016·International Journal of Neural Systems·Kostas MichalopoulosNikolaos Bourbakis
Dec 31, 2016·Journal of Alzheimer's Disease : JAD·Efraim Jaul, Oded Meiron
Dec 29, 2017·Journal of the International Neuropsychological Society : JINS·Umesh M VenkatesanWilliam C Heindel
Sep 25, 2015·Journal of Alzheimer's Disease : JAD·Marie-Pierre DeiberPanteleimon Giannakopoulos
Mar 26, 2019·Journal of Alzheimer's Disease : JAD·Michelle S GoodmanUNKNOWN PACt-MD Study Group
Nov 2, 2017·Frontiers in Aging Neuroscience·Efraim Jaul, Oded Meiron
May 2, 2018·Frontiers in Aging Neuroscience·Michelle S GoodmanTarek K Rajji
Jun 8, 2017·Frontiers in Aging Neuroscience·Lydia T NguyenJohn Hart
Oct 22, 2019·Brain : a Journal of Neurology·Sandra PusilFernando Maestú
Jun 12, 2020·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Emine Elif TülayTamer Demiralp
Apr 13, 2021·Journal of Alzheimer's Disease : JAD·Efraim Jaul, Oded Meiron
Nov 16, 2021·Frontiers in Computational Neuroscience·Nadia YoussefYingjie Li

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.

© 2021 Meta ULC. All rights reserved