Abnormal Regional Neural Activity and Reorganized Neural Network in Obesity: Evidence from Resting-State fMRI

Obesity
Peng ZhangZhen-Chang Wang

Abstract

This study aimed to investigate regional neural activity and regulation of patterns in the reorganized neural network of obesity and explore the correlation between brain activities and eating behavior. A total of 23 individuals with obesity and 23 controls with normal weight were enrolled. Functional magnetic resonance imaging (fMRI) data were acquired using 3.0-T MRI. Amplitude of low-frequency fluctuation and functional connectivity (FC) analyses were conducted using Data Processing Assistant for resting-state fMRI and Resting-State fMRI Data Analysis Toolkit (REST). The group with obesity showed increased amplitude of low-frequency values in left fusiform gyrus/amygdala, inferior temporal gyrus (ITG), hippocampus/parahippocampal gyrus, and bilateral caudate but decreased values in right superior temporal gyrus. The group with obesity showed increased FC between left caudate and right superior temporal gyrus, left fusiform gyrus/amygdala and left ITG, right caudate and left fusiform gyrus/amygdala, and right caudate and left hippocampus/parahippocampal gyrus. Dutch Eating Behavior Questionnaire-Emotional scores were positively correlated with FC between left hippocampus/parahippocampal gyrus and right caudate but negatively ...Continue Reading

References

Nov 24, 2005·Psychological Medicine·Dominic T S LeeArthur Kleinman
May 12, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·John D BeaverAndrew J Calder
Nov 23, 2006·NeuroImage·Terrence R OakesRichard J Davidson
Aug 30, 2008·Psychological Science·Suzanne HiggsGlyn W Humphreys
Jun 26, 2010·Frontiers in Systems Neuroscience·Yan Chao-Gan, Zang Yu-Feng
Apr 1, 2011·The American Journal of Clinical Nutrition·Ralph L WidyaUNKNOWN PROSPER Study Group
Jun 30, 2011·International Journal of Obesity : Journal of the International Association for the Study of Obesity·M HollmannA Horstmann
Sep 10, 2011·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·S CarnellA Geliebter
Nov 9, 2011·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A FrankortA Jansen
Apr 24, 2012·Human Brain Mapping·Isabel García-GarcíaCarme Junqué
Nov 24, 2012·Critical Reviews in Biochemistry and Molecular Biology·Dardo Tomasi, Nora D Volkow
Oct 1, 2013·Nutrition Research·Camila Oda-MontecinosAna Andrés
Aug 19, 2014·Human Brain Mapping·Stephanie KullmannHubert Preissl
Sep 30, 2014·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·I García-GarcíaJ Neumann
Jan 17, 2015·Nature·Patricia H Janak, Kay M Tye
Feb 24, 2016·Neuroscience and Biobehavioral Reviews·Savani BartholdyUlrike Schmidt
Apr 16, 2016·Psychology, Health & Medicine·Siyao WuXingwei Luo
Apr 20, 2016·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Maggie M SweitzerEric C Donny
May 3, 2016·Human Brain Mapping·Wen ZhangTianzi Jiang
Jul 4, 2016·Brain Stimulation·Marom BiksonAdam J Woods
Mar 10, 2017·Current Opinion in Endocrinology, Diabetes, and Obesity·Laura PatriarcaMiguel Alonso-Alonso
Aug 11, 2017·Scientific Reports·Bo-Yong ParkHyunjin Park
Mar 27, 2018·NeuroImage·Kayleigh Adamson, Vanessa Troiani
Apr 27, 2018·Current Diabetes Reports·Tatjana van Strien
Dec 6, 2018·Cell Reports·Jung Eun HanAlain Dagher
Dec 13, 2018·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Elena M MarronMiguel Alonso-Alonso
Jan 18, 2019·Journal of Magnetic Resonance Imaging : JMRI·Peng ZhangZhen-Chang Wang

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